肾脏透明细胞癌的部分CT征象与病理分级的相关性  

Correlation between CT features and pathological grade of clear cell renal cell carcinoma

作　　者：汪鑫斌 段润卿[2] 王灿云[1] 杨俊杰[3] 楼存诚[1] WANG Xinbin;DUAN Runqing;WANG Canyun;YANG Junjie;LOU Cuncheng(Department of Radiology,the First People's Hospital of Xiaoshan District,Hangzhou 311200,China;Department of Nuclear Medicine,the First People's Hospital of Xiaoshan District,Hangzhou 311200,China;Department of Pathology,the First People's Hospital of Xiaoshan District,Hangzhou 311200,China)

机构地区：[1]杭州市萧山区第一人民医院放射科,浙江杭州311200 [2]杭州市萧山区第一人民医院核医学科,浙江杭州311200 [3]杭州市萧山区第一人民医院病理科,浙江杭州311200

出　　处：《实用放射学杂志》2021年第6期977-979,996,共4页Journal of Practical Radiology

摘　　要：目的探讨肾脏透明细胞癌(ccRCC)的部分CT征象与病理Fuhrman分级的相关性.方法回顾性分析经手术病理证实的66例ccRCC,按病理Fuhrman分级分为低级别组(Ⅰ级和Ⅱ级)和高级别组(Ⅲ级和Ⅳ级).分析2组的CT征象特点,用χ^(2)检验和独立t检验分析2组中CT征象是否存在差异.结果低级别组(41例)和高级别组(25例)中CT表现特征瘤周短毛刺征、肾包膜凹陷征、乏血供区延迟强化、假包膜征例数分别为10例(24.3%),1例(2.4%)、7例(17.1%)、26例(63.4%);13例(52%)、2例(8%)、4例(16%)、8例(32%).高级别组瘤周短毛刺征发生率显著高于低级别组(χ^(2)=5.214,P=0.025),假包膜征发生率显著低于低级别组(χ^(2)=6.136,P=0.013),其余CT征象在高/低级别之间的差异均无统计学意义(P>0.05).结论瘤周短毛刺征的CT表现多发生于高级别ccRCC,假包膜征多发生于低级别ccRCC,此2种征象有助于术前预测ccRCC的病理分级.Objective To investigate the correlation between partial CT features of clear cell renal cell carcinoma(ccRCC)and its pathological Fuhrman grade.Methods The retrospective analysis contained 66 ccRCC patients confirmed by surgical pathology who were classified into low-grade group(GradeⅠand Grade Ⅱ)and high-grade group(GradeⅢand Grade Ⅳ)according to pathological Fuhrman grade.The CT features of low-grade group and high-grade group were analyzed.%2 test and independent samples t test were used to explore whether statistically significant differences of CT features existed between the two groups.Results The numbers of patients with CT features of peritumoral short hair marks sign,renal capsule depression.delayed enhancement of the spent blood supply area,and pseudo-capsular sign were 10,1(2.4%),7(17.1%),and 26(63.4%)in the low-grade group(41 cases)respectively,and 13(52%),2(8%),4(16%),and 8(32%)in the high-grade group(25 cases),respectively.The incidence of peritumoral short hair marks sign in the high-grade group was significantly higher than that in the low-grade group(χ^(2)=5.214,P=0.025).The incidence of pseudo-capsular sign in the high-grade group was significantly lower than that in the low-grade group(χ^(2)=6.136,P=0.013).There was no significant difference of other CT features between the two groups(P>0.05).Condusion Peritumoral short hair marks sign is common in the high-grade ccRCC.Ppseudo-capsular sign is common in the low-grade ccRCC.These two signs contribute to preoperative prediction of the pathological grade of ccRCC.

关 键 词：肾脏透明细胞癌 计算机体层成像 病理分级 

分 类 号：R737.11[医药卫生—肿瘤]