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作 者:翟媛媛[1] 柴丽君[1] 陈建中[1] ZHAI Yuanyuan;CHAI Lijun;CHEN Jianzhong(Department of Breast Surgery,The Second Affiliated Hospital of Zhengzhou University)
出 处:《长治医学院学报》2021年第3期204-207,共4页Journal of Changzhi Medical College
摘 要:目的:观察早期乳腺癌采用乳腺腔镜经腋下小切口手术治疗的临床效果。方法:回顾性分析郑州大学第二附属医院收治的45例行乳腺腔镜经腋下小切口手术治疗的早期乳腺癌患者临床资料,纳入观察组;另选取同期45例行改良根治术治疗的早期乳腺癌患者临床资料,纳入对照组。比较2组患者手术相关指标(手术时间、术中出血量、住院时间、切口长度),随访3个月,比较2组术后乳房美容效果及住院期间并发症(上肢水肿、上肢疼痛、皮肤感觉障碍)发生情况。结果:2组比较,观察组手术时间[(80.56±6.74)vs(105.64±12.34)min]、住院时间[(8.67±1.30)vs(12.58±2.03)d]短于对照组,术中出血量少于对照组[(41.25±4.36)vs(90.35±8.41)mL],切口长度短于对照组[(4.06±1.03)vs(12.14±2.33)cm],差异有统计学意义(P<0.05);术后随访3个月,观察组乳房美容优良率97.78%高于对照组的82.22%(P<0.05);观察组并发症发生率2.22%低于对照组的17.78%(P<0.05)。结论:早期乳腺癌患者采用乳腺腔镜经腋下小切口手术可有效缩短手术及住院时间,降低术中出血量,切口长度短,提高乳房美容效果,术后并发症风险较低,安全性较高。Objective:To observe the clinical effect of breast endoscopic small incision underarm surgery in the treatment of early breast cancer.Methods:A retrospective analysis of the clinical data of 45 patients with early breast cancer who underwent laparoscopic surgery through small axillary incisions admitted to the Second Affiliated Hospital of Zhengzhou University was included in the observation group;another 45 patients with early breast cancer who underwent modified radical mastectomy during the same period were selected.The clinical data of the patients were included in the control group.The operation related indicators(operation time,intraoperative blood loss,hospitalization time,incision length)were compared of patients in the two groups,followed up for 3 months,and the postoperative effect of breast beauty and the occurrence of complications(upper limb edema,upper limb pain,skin sensory disturbance)during hospitalization were compared between the two groups.Results:The operation time,hospital stay in the observation group were shorter than those in the control group,intraoperative blood loss was less than that in the control group,incision length was shorter than that in the control group,with statistical significant differences(P<0.05);after 3 months of follow-up,the excellent and good rate of breast beauty in the observation group was 97.78%,which was higher than 82.22%in the control group(P<0.05);the incidence of complications in the observation group was 2.22%,which was lower than 17.78%in the control group,with a statistical significant difference(P<0.05).Conclusion:For early breast cancer patients,the use of mammary endoscopy through small axillary incision can effectively shorten the operation and hospitalization time,reduce intraoperative blood loss,reduce the length of incision,improve effect of breast beauty.The risk of postoperative complications is lower and the safety is higher.
关 键 词:早期乳腺癌 乳腺腔镜经腋下小切口手术 基质金属蛋白酶-9 癌胚抗原 乳房美容效果
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