直肠类癌临床病理分析  

Clinical Pathology Analysis of Rectal Carcinoid

作　　者：李征[1] LI Zheng(Shandong Coal Taishan Nursing Home,Tai'an,Shandong Province,271000 China)

机构地区：[1]山东省煤炭泰山疗养院,山东泰安271000

出　　处：《系统医学》2021年第7期23-25,共3页Systems Medicine

摘　　要：目的探究直肠类癌的临床病理特征。方法选取2018年12月—2019年12月直肠类癌患者10例,将苏木精-伊红染色切片,实现免疫组化标记,辅助诊断工作的开展,对病理进行有效分析。结果在巨检下结果表现为肿物外形结节状,部分呈现出息肉状,或是呈现出黏膜局限性增厚隆起,大小在0.2~3.2 cm之间,切面颜色为灰白色,或表现为淡黄色,界限清晰,其中8例患者的肿物位置在黏膜下层,1例患者表现为侵入肌层,另外1例侵及肠壁外脂肪组织中,可检测到肿大淋巴结。在镜检结果下显示,类癌细胞多相对较小,且不同细胞的形状,染色和大小等相一致,胞浆中含有嗜酸性颗粒,细胞核为圆形,较为规则,染色质正常,少见核分裂情况,不存在坏死情况,血管较为丰富。癌细胞呈现出卵巢状和腺泡状排列情况。癌细胞组织,多在黏膜下层形成,其中有1例患者表现为癌组织侵入到细胞肌层和肠外脂肪组织中,并且1例患者呈现出淋巴结转移情况。结论就直肠类癌来说,其大多为低度恶性弥散性神经内分泌系统源性肿瘤,患者可得到较好的预后效果。可在无转移患者中将手术治疗方法进行应用,而如果患者存在转移问题,可在术后给予患者化疗干预。Objective To explore the clinicopathological characteristics of rectal carcinoid.Methods From December 2018 to December 201910 rectal carcinoids patients were selected.Hematoxylin-Eosin stained sections could realize immunohistochemical labeling,assist in the development of diagnostic work,and effectively analyzed pathology.Results Under the macro examination,the results showed that the appearance of the mass was nodular,part of it showed polypoid shape,or showed limited mucosal thickening and swelling,the size was between 0.2-3.2 cm,and the color of the cut surface was grayish white or pale yellow,with clear boundaries.The tumors in 8 patients were located in the submucosa,1 patient showed invasion of the muscle layer,and the other 1 patient invaded the fatty tissue outside the intestinal wall.Enlarged lymph nodes could be detected.The results of microscopy showed that the cancer-like cells were mostly relatively small,and the shape,staining and size of different cells were consistent.The cytoplasm contained eosinophilic granules,the nucleus was round and regular,the chromatin was normal,and nuclear divisions were rare,in this case,there was no necrosis,and the blood vessels were more abundant.The cancer cells were arranged in an ovarian and alveolar shape.Cancer tissues were mostly formed in the submucosa.Among them,one patient showed that the cancer tissue invaded the cell muscle layer and extraintestinal fat tissue,and one patient showed lymph node metastasis.Conclusion As far as rectal carcinoids are concerned,most of them are low-grade diffuse neuroendocrine system-derived tumors,and patients can get a better prognosis.Surgical treatment can be applied to patients without metastasis,and if the patient has metastasis problems,chemotherapy intervention can be given to the patient after surgery.

关 键 词：直肠类癌 病理分析 转移 化疗 

分 类 号：R735.37[医药卫生—肿瘤]