老年食管癌特征及放化疗结合与单纯放疗的效果分析  

The Characteristics of Esophageal Cancer in the Elderly and the Effect of Radiotherapy and Chemotherapy Combined with Radiotherapy Alone

作　　者：王忠强 WANG Zhongqiang(Shanxian Haijiya Hospital,Heze,Shandong Province,274300 China)

机构地区：[1]单县海吉亚医院,山东菏泽274300

出　　处：《系统医学》2021年第8期65-67,共3页Systems Medicine

摘　　要：目的探讨老年食管癌特征和放化疗结合与单纯放疗的效果。方法采用该院2017年1月—2019年12月接收的老年食管癌患者共计80例进行研究,按照抛硬币法将患者划分成对照组(40例)和研究组(40例)。对照组患者进行单纯放疗治疗,研究组使用放化疗结合治疗,归纳总结两组治疗有效率、局部控制率、总生存率、复发率、不良反应情况。结果研究组治疗有效率82.50%、局部控制率92.50%高于对照组,差异有统计学意义(χ2=5.000、4.501,P<0.05);研究组肿瘤复发率低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率和生存率比较,差异无统计学意义(P>0.05)。结论为老年食管癌患者通过放化疗结合的方式进行治疗,效果显著,可以降低术后复发率,值得临床借鉴。Objective To explore the characteristics of esophageal cancer in the elderly and the effect of radiotherapy and chemotherapy combined with radiotherapy alone.Methods A total of 80 elderly patients with esophageal cancer received in the hospital from January 2017 to December 2019 were used for the study.The patients were divided into a control group(40 cases)and a study group(40 cases)according to the coin flip method.Patients in the control group received radiotherapy alone,and the study group used a combination of radiotherapy and chemotherapy.The treatment efficiency,local control rate,overall survival rate,recurrence rate,and adverse reactions of the two groups were summarized.Results The treatment effective rate of the study group was 82.50%,and the local control rate of 92.50%were higher than that of the control group.The difference was statistically significant(χ2=5.000,4.501,P<0.05);the tumor recurrence rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05);there was no statistically significant difference in the incidence and survival rate of adverse reactions between the two groups(P>0.05).Conclusion The combination of radiotherapy and chemotherapy for elderly patients with esophageal cancer has a significant effect and can reduce the postoperative recurrence rate,which is worthy of clinical reference.

关 键 词：老年食管癌 放化疗结合 单纯放疗 

分 类 号：R735[医药卫生—肿瘤]