支架辅助弹簧圈栓塞与单纯弹簧圈栓塞治疗颅内破裂动脉瘤的疗效对比  

Comparison of the efficacy of stent-assisted coil embolization and coil embolization in the treatment of ruptured intracranial aneurysms

作　　者：马可[1] 廖晓 吕华东[1] 苏胜有 MA Ke;LIAO Xiao;LYU Hua-dong(Department of Neurology,Qinzhou First People's Hospital,Qinzhou Guangxi 535000,China)

机构地区：[1]钦州市第一人民医院神经内科,广西钦州535000

出　　处：《临床和实验医学杂志》2021年第11期1216-1219,共4页Journal of Clinical and Experimental Medicine

基　　金：广西省科学研究与技术开发计划课题(编号:20185003)

摘　　要：目的研究支架辅助弹簧圈栓塞与单纯弹簧圈栓塞治疗颅内破裂动脉瘤的疗效。方法回顾性选取2019年3月至2020年6月钦州市第一人民医院收治入院的120例颅内破裂动脉瘤患者作为研究对象,所有患者均开展血管内栓塞治疗,根据手术过程中是否选取支架辅助栓塞分为研究组(60例)与对照组(60例);研究组为支架辅助栓塞,对照组为单纯栓塞。比较2组手术前后日常生活能力评分与术后即刻动脉瘤栓塞程度、围术期不良事件发生率、复发率。结果研究组术后日常生活能力评分(58.71±4.44)分,明显高于对照组的(43.24±3.37)分,差异有统计学意义(P<0.05)。研究组Raymond分级Ⅰ级率(66.67%)明显高于对照组(46.67%),Ⅲ级率(3.33%)明显高于对照组(15.00%),差异均有统计学意义(P<0.05)。研究组出血事件发生率(1.67%)明显低于对照组(11.67%),缺血事件发生率(6.67%)明显高于对照组(0),差异均有统计学意义(P<0.05);研究组致残率(1.67%)、病死率(0%)与对照组(3.33%,1.67%)比较,差异无统计学意义(P>0.05)。研究组术后6个月复发率(3.33%)明显低于对照组(13.33%),差异有统计学意义(P<0.05)。结论颅内破裂动脉瘤治疗中支架辅助弹簧圈栓塞的应用效果明显优于单纯弹簧圈栓塞,可进一步减轻患者动脉瘤栓塞程度。Objective To study the efficacy of stent-assisted coils embolization and simple coils embolization in the treatment of intracranial ruptured aneurysms.Methods From March 2019 to June 2020,120 patients with intracranial ruptured aneurysm admitted to the Qinzhou First People's Hospital were retrospectively selected as the research objects.All patients were treated with endovascular embolization,and were divided into studies according to whether stent-assisted embolization was selected during the operation group(60 cases)and control group(60 cases);the study group was stent-assisted embolization,and the control group was embolization alone.The scores of activities of daily living before and after surgery were compared with the degree of embolization of aneurysm immediately after surgery,the incidence of perioperative adverse events,and the recurrence rate.Results The score of ability of daily living in the study group(58.71±4.44)points,which was significantly higher than that of the control group(43.24±3.37)pionts,and the difference was significant(P<0.05).The Raymond gradeⅠrate(66.67%)in the study group was significantly higher than the control group(46.67%),and theⅢgrade rate(3.33%)was significantly higher than the control group(15.00%).The differences were all significant(P<0.05).The incidence of bleeding events in the study group(1.67%)was significantly lower than that in the control group(11.67%),and the incidence of ischemic events(6.67%)was significantly higher than that in the control group(0%),and the differences were significant(P<0.05);Compared with the control group(3.33%,1.67%),the disability rate(1.67%)and death rate(0)of the study group were not significantly different(P>0.05).The recurrence rate(3.33%)of the study group at 6 months after operation was significantly lower than that of the control group(13.33%),and the difference was significant(P<0.05).Conclusion The application effect of stent-assisted coil embolization in the treatment of intracranial ruptured aneurysm is obviously better than

关 键 词：颅内动脉瘤 破裂 支架 弹簧圈 栓塞 

分 类 号：R743[医药卫生—神经病学与精神病学]