大肠腺瘤性息肉内镜治疗后复发危险因素调查研究  

Investigation of risk factors for recurrence of colorectal adenomatous polyps after endoscopic treatment

作　　者：安钰[1] 于晓兵[1] 李宏亮 王海[1] 高瑞萍[1] 李杨 AN Yu;YU Xiaobing;LI Hongliang;WANG Hai;GAO Ruiping;LI Yang(Department of Gastroenterology,People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750002,China)

机构地区：[1]宁夏回族自治区人民医院消化内科,宁夏银川750002

出　　处：《宁夏医学杂志》2021年第6期504-507,共4页Ningxia Medical Journal

基　　金：宁夏回族自治区人民医院培育振兴科研项目(201809)。

摘　　要：目的探讨大肠腺瘤性息肉内镜治疗后复发的危险因素。方法回顾性分析各种原因行内窥镜检查被诊断为大肠腺瘤性息肉510例患者的资料,对结直肠腺瘤性息肉或结直肠癌(CRC)复发者进行临床和组织学危险因素检查。结果共有190例(37.1%)患者接受结肠镜检查,其中127例(66.3%)有息肉复发。息肉数量(1~2个,≥3个,1~3个,≥4个)与糖尿病、高血压、高脂血症、性别、家族史、结肠恶性肿瘤、吸烟、饮酒、息肉大小(<10 mm,≥10 mm)或息肉的组织学类型晚期直接无相关性(P>0.05)。在基础结肠镜检查中,有130例被确诊为CRC的患者,息肉数目(1~2个)和息肉大小(≥10 mm)、贫血、高沉积率(>25%)和CRC具有较强相关性。CRC的发展与晚期组织学类型、贫血伴红细胞沉降率高、息肉大小(<10 mm,≥10 mm)和息肉数目(<3个,≥3个)之间存在显著相关性。结论左侧结肠息肉患者发生大肠息肉复发的风险较高,患有进展组织学、息肉>10 mm或多于3个息肉的患者发生CRC的风险增加。Objective To investigate the risk factors for recurrence of colorectal adenomatous polyps after endoscopic treatment.Methods 510 patients diagnosed with colorectal adenomatous polyps through endoscopy in our hospital for various reasons were retrospectively analyzed.The clinical and histological risk factors of patients with colorectal adenomatous polyps or colorectal cancer(CRC)recurrence were examined.Results 190 patients(37.1%)underwent colonoscopy.Among them,127 cases(66.3%)were found to have polyps recurrence.The number of polyps(1-2,≥3)(1-3,≥4)had no directly correlation with diabetes,hypertension,hyperlipidemia,gender,family history,colon cancer,smoking,drinking and polyp size(<10 mm,≥10mm)or the late histological type of polyp.In basic colonoscopy,130 patients were diagnosed with CRC.The number of polyps(1,2)and polyp size(≥10 mm),anemia,high deposition rate(>25)were strongly correlated with CRC.There was a significant correlation between the development of CRC and the advanced histological types,anemia with high red blood cell sedimentation rate,polyp size(<10 mm,≥10mm)and polyp number(<3,≥3).Conclusion Patients with left colon polyps have a higher risk of recurrence of colon polyps.In addition,patients with progressive histology,polyps greater than 10 mm or more than three polyps have an increased risk of CRC.

关 键 词：大肠腺瘤性息肉 复发 危险因素 

分 类 号：R574.6[医药卫生—消化系统]