不同麻醉方法对青少年复杂牙拔除术后早期记忆和认知功能的影响  

Effect of different anesthesia methods on the early memory and cognitive function of adolescents after complex tooth extraction

作　　者：李俊昌 顾英花 韦银娟 郜鑫 张晨曦[1] 闵红星 LI Junchang;GU Yinghua;WEI Yinjuan;GAO Xin;ZHANG Chenxi;MIN Hongxing(Ningxia Medical University,Yinchuan 750004,China;Department of Anesthesiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院麻醉科,宁夏银川750004

出　　处：《宁夏医学杂志》2021年第6期522-525,共4页Ningxia Medical Journal

摘　　要：目的比较丙泊酚静脉全麻与七氟烷吸入全麻对青少年复杂牙拔除术后早期记忆和认知功能的影响。方法选取在宁夏医科大学总医院口腔颌面外科行复杂牙拔除术的青少年患者60例,随机分为丙泊酚静脉全麻组(A组)和七氟烷吸入全麻组(B组),每组30例。采用Rivermead行为记忆测验(第二版)(RBMT-Ⅱ)及简易精神量表(MMSE)于术前1 d(T1)及术后1 d(T2)、术后2 d(T3)对2组患者记忆功能与精神状态进行评分,观察比较2组患者不同时间点的量表评分情况。结果2组患者一般资料相比差异无统计学意义,与B组相比,A组T2时RBMT-Ⅱ评分高于B组(P<0.05);但在T3时2组患者的RBMT-Ⅱ评分差异无统计学意义,在T3与T1时RBMT-Ⅱ评分差异无统计学意义。与B组相比,A组在T2时MMSE评分有明显升高(P<0.05),且2组患者在T3时MMSE评分与T1评分相比差异无统计学意义。同时2组患者在T2时RBMT-Ⅱ及MMSE评分均较T1降低(P<0.05)。结论七氟烷吸入与全麻相比,丙泊酚静脉全麻对复杂牙拔除术的青少年患者术后早期记忆功能与认知功能影响较小。Objective To compare the effects of propofol intravenous general anesthesia and sevoflurane inhaled general anesthesia on early memory and cognitive function after complex tooth extraction in adolescents.Methods 60 adolescent patients who underwent complex tooth extraction in the department of oral and maxillofacial surgery of Ningxia Medical University were randomly divided into propofol intravenous anesthesia group(group A)and sevoflurane anesthesia group(Group B),30 cases in each group.Rivermead behavior memory test second edition(RBMT-Ⅱ)and mini mental scale(MMSE)were used to evaluate the efficacy of propofol intravenous anesthesia on the 1st day before surgery(T1),1st day after surgery(T2),2nd after surgery Day(T3).The memory function and mental state of the two groups were evaluated.The scale scores of the two groups at different time points were observed and compared.Results There was no statistically significant difference in general information between the two groups.Compared with group B,the T2RBMT-Ⅱ score of group A was higher than that of group B(P<0.05).However,there was no statistical difference in the RBMT-Ⅱ score between the two groups at T3.At the same time,there was no statistically significant difference in RBMT-Ⅱ scores between the two groups at T3 and T1.Compared with group B,the T2 and T3 MMSE scores of group A were significantly improved compared with group B(P<0.05),and there was no statistically significant difference between the two groups in T3 MMSE score and T1 score.At the same time,the RBMT-Ⅱ and MMSE scores of T2 in the two groups were lower than those of T1(P<0.05).Conclusion Compared with sevoflurane inhalation anesthesia,propofol intravenous anesthesia has less effect on early postoperative memory function and cognitive function of adolescent patients with complex tooth extraction.

关 键 词：麻醉药 青少年 认知功能 记忆功能 

分 类 号：R614[医药卫生—麻醉学]