医学图像处理MIM软件和Velocity软件在弹性模体中形变配准精度的比较研究  

Comparative study on the registration accuracy of image deformation in elastic motif between MIM software and Velocity software of medical image process

作　　者：劳峥 樊文慧 毕帆 石慧烽[1] 涂文勇[1] 胡海生[1] LAO Zheng;FAN Wen-hui;BI Fan(Department of Oral Maxillofacial Head and neck Oncology,College of Stomatology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,Shanghai 200011,China.)

机构地区：[1]上海交通大学医学院附属第九人民医院,口腔医学院,口腔颌面头颈肿瘤科,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室上海市口腔医学研究所,上海200011

出　　处：《中国医学装备》2021年第6期47-51,共5页China Medical Equipment

基　　金：上海黄浦区产业扶持基金(XK2020012)“三维个体化空腔模体转化研究”。

摘　　要：目的:评价两种医学图像处理软件(MIM软件和Velocity软件)在弹性模体中的形变配准精度。方法:采用印模膏捏制长方形、正方形及圆形3个不同形状的物体置于琼脂糖凝胶中,制备成含有3个不同形状印模膏物体可弯曲的弹性模体,通过CT对该模体在平直状态下和形变后的弯曲状态下分别进行定位扫描,将形变弯曲前后的两组CT影像数据均导入MIM软件和Velocity软件中,在形变前后的两组CT图像中,均对弹性模体所含的3个印模膏物体行靶区勾画后再进行形变配准,通过计算印模膏物体在MIM软件和Velocity软件中的相似性系数(Dice系数)和豪斯多夫距离(Hausdorff距离),评价MIM软件和Velocity软件对弹性模体形变配准的精度。结果:不同形状印模膏物体可弯曲弹性模体在平直状态下、形变后弯曲状态下扫描得到两组CT图像,经过MIM软件和Velocity软件形变配准处理后,3个不同形状印模膏物体的Dice系数和Hausdorff距离两组间比较,差异无统计学意义(t_(Dice系数)=-0.179,t=1.231,t=2.663;t_(Hausdorff距离)=1.295,t=0.126,t=-1.84;P>0.05)。结论:MIM软件和Velocity软件的形变配准精度无显著差异,两者都较好地具备了多模态影像形变配准的能力,均能满足临床放射治疗图像处理的需要,而MIM软件在实践操作中相对更简便、快捷。Objective:To evaluate the difference of registration accuracy of image deformation in elastic phantom between two kinds of medical image processing softwares(MIM software and Velocity software).Methods:Modelling compound was adopted to product 3 objects that were different shapes(rectangle,square and round)and put them in agarose gel so as to product flexional elastic motif that contained three modelling compound objects that were 3 different shapes.The located scan was implemented on motifs by computed tomography(CT)under straightness condition and flexuosity post deformation.Both two groups of CT image data pre and post deformation were imported to MIM software and Velocity software.In the two groups of CT images pre and post deformation,the three modelling compounds in elastic motifs were implemented deformation registration after they were drawn the outline of target region.The precisions of MIM software and Velocity software on deformation registration of elastic motifs were evaluated by calculating the similarity coefficient(Dice coefficient)and Hausdorff distance of modelling compound objects in MIM software and Velocity software.Results:The flexible elastic motifs of modelling compound objects with different shapes could obtain two groups of CT images under straightness condition and flexuosity post deformation.The differences of Dice efficient and Hausdorff distance of 3 modelling compound objects with different shapes,which were processed by deformation registration via MIM software and Velocity software,were not significant(tDice efficient=-0.179,t=1.231,t=2.663,tHausdorff distance=1.295,t=0.126,t=-1.84,P>0.05).Conclusion:There is no significant difference in the accuracy of deformation registration between MIM software and Velocity software.Both of them have the ability of deformation registration of multi-modality image and can meet the requirement of image processing of clinical radiotherapy.MIM software is relatively simpler and faster in practical operation.

关 键 词：图像融合 形变配准 相似性系数(Dice系数) 豪斯多夫距离(Hausdorff距离) 弹性模体 

分 类 号：R-058[医药卫生]