腹腔镜下广泛子宫切除术联合盆腔淋巴结切除治疗早期宫颈癌的预后效果及对盆底肌功能的影响  

Prognostic effect of laparoscopic extensive hysterectomy combined with pelvic lymph node resection on early cervical cancer and the influence of pelvic floor muscle function

作　　者：王倩 陈炎[2] 陈红梅 WANG Qian;CHEN Yan;CHEN Hongmei(Department of Gynecology and Obstetrics,Bozhou Hospital of Traditional Chinese Medicine,Anhui Province,Bozhou236800,China;Department of Gynecology and Obstetrics,the First Affiliated Hospital of Anhui Medical University,Anhui Province,Hefei230031,China)

机构地区：[1]安徽省亳州市中医院妇产科,安徽亳州236800 [2]安徽医科大学第一附属医院妇产科,安徽合肥230031

出　　处：《中国医药导报》2021年第18期103-106,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81272881)。

摘　　要：目的探讨腹腔镜下广泛子宫切除术联合盆腔淋巴结切除治疗早期宫颈癌的预后效果及对盆底肌功能的影响。方法回顾性分析2016年12月—2019年12月安徽省亳州市中医院妇产科行手术治疗的80例早期宫颈癌患者的临床资料,根据手术方法将其分为观察组和对照组,各40例。观察组采用腹腔镜下广泛子宫切除术联合盆腔淋巴结切除治疗,对照组给予常规开腹广泛子宫切除术联合盆腔淋巴结切除治疗,术后对患者进行随访,比较两组患者癌症治疗功能总体评价量表(FACT-G)评分,术后半年、1年生存率,术后1年内复发率,盆底肌肌力测定正常率,女性性功能量表(FSFI)评分及性功能障碍发生率。结果术后1年,观察组FACT-G评分高于对照组,差异有高度统计学意义(P<0.01)。两组术后半年、1年生存率及术后1年内复发率比较,差异无统计学意义(P>0.05)。观察组盆底肌肌力测定正常率、FSFI评分均高于对照组,差异有统计学意义(P<0.05或P<0.01);性功能障碍发生率低于对照组,差异有高度统计学意义(P<0.01)。结论腹腔镜下广泛子宫切除术联合盆腔淋巴结切除治疗早期宫颈癌预后效果与开腹手术相当,患者生存质量显著提高,术后盆底功能的恢复较好,值得临床上推广应用。Objective To explore the prognostic effect of laparoscopic extensive hysterectomy combined with pelvic lymph node resection on early cervical cancer and the influence of pelvic floor muscle function.Methods Retrospective analysis was made on the clinical data of 80 patients with early cervical cancer who underwent surgical treatment were selected in Department of Gynecology and Obstetrics,Bozhou Hospital of Traditional Chinese Medicine,Anhui Province from December 2016 to December 2019.According to surgical methods,they were divided into observation group and control group,with 40 cases in each group.Observation group was treated with laparoscopic extensive hysterectomy combined with pelvic lymph node resection,while control group was treated with conventional laparotomy extensive hysterectomy combined with pelvic lymph node resection.After the operation,the patients were followed up,the functional assessment of cancer therapy-general(FACT-G)score,half a year and one year survival rate after surgery,recurrence rate within one year after surgery,normal rate of pelvic floor muscle strength,female sexual function index(FSFI)score and incidence of sexual dysfunction were compared between two groups.Results One year after surgery,FACT-G score of observation group was higher than that of control group,and the difference was highly statistically significant(P<0.01).There were no significant differences between two groups in half a year,one year survival rate after surgery,and recurrence rate within one year after surgery(P>0.05).The normal rate of pelvic floor muscle strength and FSFI score in observation group were higher than those in control group,and the differences were statistically significant(P<0.05 or P<0.01);the incidence of sexual dysfunction was lower than that of control group,and the difference was highly statistically significant(P<0.01).Conclusion Laparoscopic extensive hysterectomy combined with pelvic lymph node resection in the treatment of early cervical cancer has the same prognosis as laparotomy.Th

关 键 词：腹腔镜 广泛子宫切除 盆腔淋巴结切除 盆底肌功能 

分 类 号：R737.33[医药卫生—肿瘤]