超声影像方法在预测HIFU治疗子宫肌瘤疗效中的应用  

Application of ultrasonography in predicting the HIFU therapeutic efficacy on uterine leiomyoma

作　　者：姚一静 姜立新[1] YAO Yijing;JIANG Lixin(The Department of Ultrasound in medicine,Shanghai Jiaotong University Affiliated Sixth People’s Hospital,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院,上海200233

出　　处：《声学技术》2021年第3期376-380,共5页Technical Acoustics

基　　金：国家自然科学基金资助项目(81771850);上海交通大学医工交叉项目(YG2017MS19)。

摘　　要：子宫肌瘤是育龄期女性最常见的良性肿瘤,高强度聚焦超声(High Intensity Focused Ultrasound,HIFU)作为一种微创治疗技术,已经广泛运用于子宫肌瘤的治疗,但是对于某些特殊类型的肌瘤消融效率较低,并导致很多严重的并发症。这类肌瘤在二维灰阶超声、多普勒超声、超声造影方面有特殊的表现。对上述超声影像方法在预测HIFU治疗子宫肌瘤疗效中的作用进行了综述。但各种超声影像学技术存在一定误差,提供子宫肌瘤内部微血管灌注信息仍不完全,在未来研究中可使用包括微血管成像技术(Superb Micro-vascular Imaging,SMI)、造影剂微血管灌注成像(Contrast Micro-Imaging,CMI)、磁共振成像(Magnetic Resonance Imaging,MRI)多种技术在内的多模态分析,为HIFU治疗子宫肌瘤疗效预测提供更多参考和信息。Uterine leiomyoma is the most common benign tumor in women of childbearing age.As a minimally invasive treatment technique,the high-intensity focused ultrasound(HIFU)has been widely used in the treatment of uterine leiomyoma,but the ablation efficiency is low for some special types of leiomyoma,so as to cause a lot of serious complications.This kind of leiomyoma has its special manifestations in the images of two-dimensional gray-scale ultrasound,Doppler ultrasound and contrast-enhanced ultrasound.A review of the role of the above ultrasound imaging methods in predicting the efficacy of HIFU treating uterine leiomyoma is made in this article.However,there are certain errors in various ultrasound imaging techniques,and the information of microvascular perfusion in uterine leiomyoma is still incomplete.To provide more reference and information for predicting the efficacy of HIFU treating uterine leiomyoma,multimodal analysis including superb micro-vascular imaging(SMI),contrast micro-imaging(CMI)and magnetic resonance imaging(MRI)can be used in future research.

关 键 词：超声 高强度聚焦超声 子宫肌瘤 疗效预测 

分 类 号：R737.33[医药卫生—肿瘤]