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作 者:郭文 吴思缈[1] 刘鸣[1] GUO Wen;WU Simiao;LIU Ming(Department of Neurology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)
出 处:《华西医学》2021年第6期701-706,共6页West China Medical Journal
基 金:国家自然科学基金(81974181);四川省科学技术厅应用基础研究项目(2021YJ0433);四川大学华西医院学科发展1·3·5工程项目(ZYGD18009)。
摘 要:大面积和重症脑梗死致死致残率高,是目前脑血管病防治的瓶颈。大面积脑梗死的恶性脑水肿和重症脑梗死的危重症状态一旦发生,治疗效果极差。因此对危重症脑梗死不仅要加强治疗,更应预防其发生。关口前移、提前预防这种危重状况发生以及更前移的预防大面积脑梗死和重症脑梗死发生具有更加重要的临床意义。该文指出一些大面积或重症脑梗死患者是可以预防其进展为危重症的;提出了危重症脑梗死的定义及关键危险因素和相应防治要点;危重症脑梗死可分为伴恶性脑水肿或不伴恶性脑水肿2类,可各有侧重地研究其危险因素及分类分期预测预防策略。Massive and severe cerebral infarction can lead to a high mortality and disability rate,and it is the bottleneck of preventing and treating cerebrovascular disease.Once the malignant brain edema of massive cerebral infarction or the critical status of severe cerebral infarction occurs,the treatment effect is very poor.Therefore,we should not only focus on the treatment of critical cerebral infarction,but also prevent its occurrence.It is clinically important to prevent the occurrence of this critical condition in advance and to prevent the occurrence of massive cerebral infarction and severe cerebral infarction.This article points out that some patients with massive or severe cerebral infarction can be prevented from becoming critically ill.The definition,key risk factors and corresponding prevention and treatment strategies of critical cerebral infarction have also been proposed.Critical cerebral infarction can be divided into two categories with or without malignant brain edema,and the risk factors and prediction and prevention strategies by categories and phases can be studied separately.
关 键 词:危重症脑梗死 恶性脑水肿 大面积脑梗死 重症脑梗死 分类分期预防
分 类 号:R743.33[医药卫生—神经病学与精神病学]
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