高分辨磁共振技术在颅内动脉粥样硬化疾病的临床应用  

High-resolution magnetic resonance imaging in intracranial atherosclerotic disease

作　　者：袁伟壮 徐蔚海 YUAN Weizhuang;XU Weihai(Department of Neurology,State Key Laboratory of Complex Severe and Rare Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,P.R.China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院神经科,疑难重症及罕见病国家重点实验室,北京100730

出　　处：《华西医学》2021年第6期707-713,共7页West China Medical Journal

摘　　要：近年来,高分辨磁共振(high-resolution magnetic resonance imaging,HRMRI)已成为临床和研究的有用工具。利用HRMRI可以在活体内观察到颅内血管壁病变,提供了更多有价值的病理生理学信息,对颅内动脉粥样硬化疾病的诊断、鉴别诊断及预后判断提供了指导。对于狭窄性颅内血管动脉粥样硬化,管壁形态能有效鉴别不同血管狭窄疾病,而斑块成分、强化模式、重构方式等对斑块易损性有一定提示意义。对于非狭窄性颅内血管动脉粥样硬化,通过斑块位置也可揭示背后的病理生理机制。此外,通过HRMRI可显示病变的豆纹动脉。因此,该文将对HRMRI临床应用进行总结。In recent years,high-resolution magnetic resonance imaging(HRMRI)has become a useful clinical and research tool.HRMRI can be used to observe intracranial vascular wall lesions in vivo,providing more valuable pathophysiological information,and providing guidance for the diagnosis,differential diagnosis and prognosis of intracranial atherosclerosis.For stenotic intracranial atherosclerosis,the morphology of the vessel wall can effectively differentiate various vascular stenosis diseases.Further,plaque composition,vessel wall enhancement,remodel mode provide information of plaque vulnerability.For non-stenotic intracranial atherosclerosis,the location of the plaque can reveal the pathophysiological mechanism.In addition,HRMRI can show the lesion in lenticulostriate artery.Therefore,this article will summarize the clinical application of HRMRI.

关 键 词：脑卒中 动脉粥样硬化 高分辨磁共振 

分 类 号：R743.3[医药卫生—神经病学与精神病学]