脑微梗死的检测及与缺血性脑卒中患者的相关性研究进展  

Detection of cerebral microinfarction and research progress of its correlation with patients with ischemic stroke

作　　者：陶文丹[1,2] 刘峻峰[1,2] 吴波[1,2] 刘鸣[1,2] TAO Wendan;LIU Junfeng;WU Bo;LIU Ming(Department of Neurology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China;Cerebrovascular Center,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)

机构地区：[1]四川大学华西医院神经内科,成都610041 [2]四川大学华西医院脑血管病研究中心,成都610041

出　　处：《华西医学》2021年第6期808-811,共4页West China Medical Journal

基　　金：国家自然科学基金(81601022);四川大学华西医院学科发展1·3·5工程项目(ZYGD18009)。

摘　　要：脑微梗死被认为是缺血性脑小血管病的一种表现形式,既往认为其与脑血管病和痴呆密切相关。随着影像技术的进步,高分辨率MRI被发现可在活体中检出微梗死。目前研究显示脑微梗死不仅在痴呆患者和老年人群中常见,在缺血性脑卒中患者中同样存在。该文基于近期发表的微梗死在缺血性脑卒中患者中的MRI研究报道,对微梗死的检出率、危险因素和病因以及预后进行综述,旨在为缺血性脑卒中微梗死相关脑损害防治策略的制定提供新思路。Cerebral microinfarcts are presumed to be a manifestation of ischemic cerebral small vessel disease.It is presumed to have close relationship with dementia and cerebrovascular disease.With the advancement of imaging technology,high-resolution MRI has been found to detect microinfarctions in vivo.Current studies have shown that cerebral microinfarctions are not only commonly in individuals with dementia and elderly with normal aging,but also in patients with ischemic stroke.Based on the recently published MRI studies of microinfarcts in ischemic stroke patients,this paper summarizes the detection rate,risk factors,etiology and prognosis of cerebral microinfarcts,and aims to provide new ideas for the formulation of prevention and treatment strategies of cerebral microinfarcts related brain damage in ischemic stroke patients.

关 键 词：脑微梗死 磁共振成像 脑卒中 

分 类 号：R743.3[医药卫生—神经病学与精神病学]