肺癌化疗患者5次坐立试验水平与疲乏的关系  

Correlational analysis of the five-times-sit-to-stand test and cancer-related fatigue in patients with lung cancer during chemotherapy

作　　者：吴振云[1] 徐佳丽[1] 叶烨秋 赵茜 钱红英[1] WU Zhen-yun;XU Jia-li;YE Ye-qiu;ZHAO Qian;QIAN Hong-ying(Department of Respiratory,the First Affiliated Hospital of Soochow University,Soochow 215006,Jiangsu,China)

机构地区：[1]苏州大学附属第一医院呼吸科,苏州215006

出　　处：《医学研究生学报》2021年第6期609-614,共6页Journal of Medical Postgraduates

基　　金：苏州市科技发展计划项目(SYSD2014082);苏州大学附属第一医院周氏基金项目(HLYJ-Z-2018-04)。

摘　　要：目的目前,肺癌患者的评估集中于疾病症状、生活质量及预后等方面,缺乏对肺癌患者日常活动功能等的关注。文中调查分析肺癌化疗患者5次坐立试验(FTSST)水平现状及其与疲乏症状的关系。方法选取2019年1月-2020年3月入住我院的103例肺癌化疗患者作为研究对象。采用一般情况调查表、Piper疲乏修正量表以及FTSST对患者进行评估调查,并分析FTSST水平与疲乏间的关系。结果肺癌化疗患者FTSST为(8.35±2.77)s,疲乏总分为(4.26±1.98),整体处于中度疲乏状态。FTSST与疲乏各维度呈轻中度正相关(r=0.350~0.501,P<0.01)。多元线性回归分析结果显示,情感疲乏(X_(1))、有无合并症(X_(2))、职业(X_(3))以及PS评分(X_(4))4个因子可解释FTSST水平41.1%的变异程度,多元线性回归方程为Y=6.235+0.466X_(1)+1.378X_(2)-0.519X 3+0.905X_(4)。将情感疲乏变量从模型中移除,解释变异程度降至29.5%;若将PS体力状况移除,解释变异程度下降至36.7%。结论肺癌化疗患者FTSST与疲乏症状相关,且情感疲乏及PS评分影响患者的FTSST水平。Objective To date,assessment of patients with lung cancer have focused on their symptoms,living quality and prognosis,while scant attention has been paid on their daily activities.The purpose of this study was to establish the relationship between the five-times-sit-to-stand test(FTSST)and cancer-related fatigue(CRF)in patients with lung cancer during chemotherapy.Methods A total of 103 cases of lung cancer patients admitted to the hospital from January 2019 to March 2020 were selected as the study subjects.A questionnaire form,the revised piper fatigue scale and FTSST were adopted to assess the patients.The relationship between FTSST and CRF was analyzed.Results The FTSST in patients with lung cancer during chemotherapy was(8.35±2.77)s,and the overall score of fatigue was(4.26±1.98),showing moderate fatigue status.The scores in different dimensions of CRF were slightly/moderately correlated with FTSST(r=0.350~0.501,P<0.01).Multivariate linear regression analysis exhibited emotional fatigue(X 1),complications(X 2),occupations(X 3)and performance status(X 4)could be taken as predictive factors for the variation degree of FTSST(R^(2)=41.1%),and the equation was Y=6.235+0.466X 1+1.378X 2-0.519X 3+0.905X 4.The variation degree decreased to 29.5%when the emotional fatigue was removed from the model,and 36.7%when the PS was removed.Conclusion The FTSST in patients with lung cancer during chemotherapy is closely associated with fatigue,and emotional fatigue and PS affect the FTSST.

关 键 词：肺癌 5次坐立试验 下肢功能 疲乏 

分 类 号：R734.2[医药卫生—肿瘤]