老年脑梗死继发全身炎症反应综合征对预后的影响及其危险因素分析  

Prognostic effect and risk factors of systemic inflammatory response syndrome secondary to cerebral infarction in the elderly

作　　者：陆瑜 黄培培[2] Lu Yu;Huang Pei-pei(Jiangsu Shengze Hospital ICU Wuxi Wuxi 215228,China;Jiangsu Province Hospital The Emergency Department,Nanjing 215228,Chirui)

机构地区：[1]江苏盛泽医院ICU,无锡215228 [2]江苏省人民医院急诊科,南京210029

出　　处：《湖南师范大学学报（医学版）》2021年第1期172-175,共4页Journal of Hunan Normal University(Medical Sciences)

摘　　要：目的:探讨老年脑梗死继发全身炎症反应综合征对预后的影响及其危险因素。方法:选取2015年6月~2018年7月在我院治疗的老年脑梗死患者130例,收集分析患者临床资料。结果:130例老年脑梗死患者中,继发全身炎症反应综合征发生率为36.92%;继发全身炎症反应综合征患者发病后21d死亡率为47.92%,明显高于未继发全身炎症反应综合征患者;继发全身炎症反应综合征患者糖尿病病史、空腹血糖、入院NIHSS评分、完全前循环梗死、梗死面积≥1/2半球的比例分别为45.83%、(6.70±1.22)mmol/L、(12.12±2.03)分、60.42%和62.50%,明显高于未继发全身炎症反应综合征患者;Logistic回归分析结果显示:糖尿病病史、入院NIHSS评分、完全前循环梗死、梗死面积≥1/2半球是发生全身炎症反应综合征的危险因素(OR=2.469、3.673、2.907和3.071)。结论:老年脑梗死继发全身炎症反应综合征患者死亡率高,继发全身炎症反应综合征受多种因素影响,临床救治时应加以重视。Objective To investigate the prognostic effect and risk factors of systemic inflammatory response syndrome secondary to cerebral infarction in the elderly.Methods 130 elderly patients with cerebral infarction treated in our hospital from June 2015 to July 2018 were selected,the clinical data of patients were collected and analyzed.Results In 130 elderly patients with cerebral infarction,the incidence of secondary systemic inflammatory response syndrome was 36.92%;The mortality rate of patients with secondary systemic inflammatory response syndrome at 21 days after onset was 47.92%,which was significantly higher than that of patients without secondary systemic inflammatory response syndrome;The proportion of diabetes history,fasting blood sugar,NIHSS score,complete anterior circulation infarction,infarct area ≥1/2 hemisphere in patients with secondary systemic inflammatory response syndrome were 45.83%,(6.70±1.22) mmol/L,(12.12±2.03),60.42% and 62.50%,which were significantly higher than those in patients without secondary systemic inflammatory response syndrome;Logistic regression analysis showed that history of diabetes mellitus,NIHSS score at admission,complete anterior circulation infarction,infarct size ≥1/2 hemisphere were risk factors for systemic inflammatory response syndrome (OR=2.469,3.673,2.907 and 3.071).Conclusion Senile patients with cerebral infarction secondary to systemic inflammatory response syndrome have a high mortality rate,secondary systemic inflammatory response syndrome is affected by many factors,so should pay attention to it in clinical treatment.

关 键 词：老年 脑梗死 全身炎症反应综合征 预后 危险因素 

分 类 号：R746.1[医药卫生—神经病学与精神病学]