简化老年综合评估分级在老年女性乳腺癌患者中的应用价值  

Application Value of Abbreviated Comprehensive Geriatric Assessment in Elderly Female Breast Cancer Patients

作　　者：林燕[1] 宋雨 徐颖[1] 姚儒[1] 周星彤 王常珺[1] 黄欣[1] 王雪霏[1] 曹希[1] 孙强[1] LIN Yan;SONG Yu;XU Ying;YAO Ru;ZHOU Xingtong;WANG Changjun;HUANG Xin;WANG Xuefei;CAO Xi;SUN Qiang(Department of Breast Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院乳腺外科,北京100730

出　　处：《中国医学科学院学报》2021年第3期395-401,共7页Acta Academiae Medicinae Sinicae

摘　　要：目的评估简化老年综合评估(aCGA)分级在老年女性乳腺癌患者中应用价值。方法将综合老年评估(CGA)8个方面的简化量表内容和得分纳入aCGA评估表,根据评估得分划分为A、B、C 3个级别。以2018年6月至2020年1月北京协和医院收治的70岁及以上的老年女性乳腺癌患者为研究对象,分别做美国东部肿瘤协作组(ECOG)评分及aCGA分级,并对两种评估方法的结果进行比较。结果162例患者中,111例(68.5%)aCGA分级为A级,43例(26.5%)为B级,8例(5.0%)为C级;131例(80.9%)伴有并发疾病,最常见的并发症依次为高血压(n=89)、心血管疾病(n=47)、糖尿病(n=39)。ECOG评分0~1分133例(82.0%),2分24例(14.8%),3分5例(3.2%),无4分及以上病例。ECOG体能状态良好133例(82.0%),不良29例;aCGA分级健康状态良好111例,不良51例;两组相比差异有统计学意义(χ^(2)=14.24,P<0.001)。结论aCGA分级较ECOG评分能更全面评估老年女性乳腺癌患者的综合健康状况,可应用于70岁及以上的老年乳腺癌患者。Objective To evaluate the application value of abbreviated comprehensive geriatric assessment(aCGA)in elderly female breast cancer patients.Methods Eight aspects of the traditional CGA were simplified to form the aCGA assessment table,based on which the patients were classified into three grades of A,B and C according to the total scores.This study enrolled the elderly female patients with breast cancer aged 70 years and above who were treated in PUMC Hospital from June 2018 to January 2020.Eastern Cooperative Oncology Group(ECOG)scoring and aCGA grading were performed respectively,and the results of the two methods were compared.Results Of the 162 patients,111(68.5%)were classified by the aGGA method as grade A,43(26.5%)as grade B,and 8(5.0%)as grade C;131(80.9%)cases have concurrent diseases,and the most common complications were hypertension(n=89),cardiovascular diseases(n=47)and diabetes mellitus(n=39).The ECOG score was 0-1 in 133(82.0%)cases,2 in 24(14.8%)cases and 3 in 5(3.2%)cases.The ECOG score showed 133(82.0%)cases with good status and 29 cases with poor status.However,according to the aCGA classification,111 cases were in good health status and 51 cases were in poor health status;the difference in the result between the two groups was statistically significant(χ^(2)=14.24,P<0.001).Conclusion Compared with ECOG score,aCGA grading can more comprehensively evaluate the health status of elderly female breast cancer patients and can be applied to the patients aged 70 and above.

关 键 词：老年 乳腺癌 综合评估 东部肿瘤协作组评分 

分 类 号：R737.9[医药卫生—肿瘤]