胃黏膜肠上皮化生的研究进展  

Research progress of gastric intestinal metaplasia

作　　者：黄倩 李学良[1] HUANG Qian;LI Xueliang(Department of Gastroenterology,First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,210029)

机构地区：[1]南京医科大学第一附属医院消化内科,江苏南京210029

出　　处：《实用临床医药杂志》2021年第9期107-112,共6页Journal of Clinical Medicine in Practice

摘　　要：胃黏膜肠上皮化生(IM)是指胃黏膜上皮细胞被肠型上皮细胞所代替的一种病理形态学改变。IM被普遍视为胃癌(尤其是肠型胃癌)的前兆,受到广泛关注。近年来,国内外学者在IM的组织特征、发病因素与机制、检测、诊断和治疗等方面进行了大量研究。本文就上述方面对IM的研究进展进行综述,旨在加深临床对IM的认识,为IM以及早期胃癌的监测与预防提供参考。Gastric intestinal metaplasia(IM)a pathomorphologic change in which gastric mucosal epithelial cells are replaced by intestinal epithelial cells.IM is widely regarded as the precursor of gastric cancer(especially intestinal gastric cancer)and has attracted wide attention.In recent years,scholars at home and abroad have conducted a large number of studies on the organizational characteristics,pathogenic factors and mechanisms,detection,diagnosis and treatment of IM.This paper reviewed the research progress of IM in the above aspects,aiming to deepen the clinical understanding of IM,and provide reference for the monitoring and prevention of IM and early gastric cancer.

关 键 词：肠上皮化生 发病因素及机制 监测 早期胃癌 

分 类 号：R573.3[医药卫生—消化系统] R735.2[医药卫生—内科学]