金纳米颗粒在牙周病预防及治疗中的研究进展  

Research progress of gold nanoparticles in prevention and treatment of periodontal disease

作　　者：田密 高尚 周珊[1] 王晓峰[1] 刘杰[1] TIAN Mi;GAO Shang;ZHOU Shan;WANG Xiaofeng;LIU Jie(Department of Stomatology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150000)

机构地区：[1]哈尔滨医科大学附属第二医院口腔科,黑龙江哈尔滨150000

出　　处：《实用临床医药杂志》2021年第9期123-127,共5页Journal of Clinical Medicine in Practice

基　　金：国家自然科学基金资助项目(81672827)。

摘　　要：牙周病治疗的主要目标是修复损伤组织以及控制疾病传播。目前,牙周病的传统临床治疗效果均有限。金纳米颗粒(Au NPs)具有独特的光学性质、良好的生物相容性、易于合成和功能化等优点,已成为临床上实现生物成像、药物输送、疾病诊断和治疗的有前景的纳米材料。本文就金纳米在牙周疾病预防及治疗中的应用进行综述,以为牙周病的预防以及治疗提供新的方向。The main goals of treatment for periodontal disease are to repair damaged tissue and control the spread of the disease.At present,the effect of traditional clinical treatment of periodontal disease is limited.Gold nanoparticles(Au NPs)have been a promising nanomaterial for clinical application in biological imaging,drug delivery,disease diagnosis and treatment due to their unique optical properties,good biocompatibility,easy synthesis and functionalization.In this paper,the application of gold nanometer in the prevention and treatment of periodontal disease was reviewed,in order to provide a new direction for the prevention and treatment of periodontal disease.

关 键 词：金纳米 牙周病 成骨 抑菌 组织工程 

分 类 号：R318.08[医药卫生—生物医学工程] R784.1[医药卫生—基础医学]