T淋巴母细胞淋巴瘤肾脏浸润患者^(18)F-FDG PET/CT影像分析  

Study of ^(18)F-FDG PET/CT findings of T-lymphoblastic lymphoma with renal infiltration

作　　者：谢新立[1] 刘艳[1] 程兵[1] 韩星敏[1] XIE Xinli;LIU Yan;CHENG Bing;HAN Xingmin(Department of Nuclear Medicine,the First Affiliated Hospital of Zhengzhou University,Henan Provincial Key Laboratory of Molecular Imaging,Henan Zhengzhou 450052,China.)

机构地区：[1]郑州大学第一附属医院核医学科,河南省分子影像重点实验室,河南郑州450052

出　　处：《现代肿瘤医学》2021年第13期2334-2337,共4页Journal of Modern Oncology

基　　金：河南省科技攻关项目(编号:201503068)。

摘　　要：目的:探讨T淋巴母细胞淋巴瘤合并肾脏浸润患者^(18)F-FDG PET/CT影像学特征。方法:回顾性分析2011年01月至2020年01月我院7例T淋巴母细胞淋巴瘤合并肾脏浸润患者的^(18)F-FDG PET/CT影像,其中男性6例,女性1例;年龄范围5~27岁,平均年龄(16.1±7.4)岁。使用Siemens Biograph TruePoint 64(52环)PET/CT仪显像,分析7例患者肾脏浸润形态学表现并计算最大标准化摄取值(SUVmax),并对全身其他部位淋巴瘤浸润的情况进行分析。结果:7例患者13个肾脏受累,以双肾体积增大伴FDG弥漫性摄取增高4例(4/7,57.1%),SUVmax为14.4±9.2,双肾实质密度正常或普遍稍减低;以双肾多发结节状FDG摄取增高灶2例(2/7,28.6%),结节长径约0.7~1.7 cm,SUVmax为11.1±4.4;以单发结节状FDG摄取增高灶1例(1/7,14.3%),结节长径约1.2 cm,SUVmax 13.5;7例患者肾脏病灶平均SUVmax为13.34±6.93;肾脏弥漫性浸润患者与结节状浸润患者之间差异无统计学意义(Z=-0.354,P=0.724)。结论:T淋巴母细胞淋巴瘤肾脏浸润以双肾体积增大伴FDG摄取弥漫性增高为较常见的表现,有一定的特征性。Objective:To investigate the imaging features of^(18)F-FDG PET/CT in T-lymphoblastic lymphoma(T-LBL)with renal infiltration.Methods:Seven patients,6 males,1 female,average age(16.1±7.4)years with T-LBL,who had definitive renal infiltration by^(18)F-FDG PET/CT or pathological results from January 2011 to January 2020,were analyzed retrospectively.The changes of kidney shape,density and the whole body infiltration were evaluated and the maximum standardized uptake values(SUVmax)were calculated.Results:Thirteen kidneys of 7 patients were involved.Four cases(4/7,57.1%)of them had increased volume of both kidneys with increased diffuse FDG uptake,and SUVmax was 14.4±9.2.The density of parenchyma of both kidneys was normal or generally slightly decreased.Two cases(2/7,28.6%)had increased FDG uptake in multiple nodules of both kidneys,and the size of the nodules was about 0.7~1.7 cm,the SUVmax was 11.1±4.4.One case(1/7,14.3%)showed single nodular FDG uptake increased.The size of nodule was about 1.2cm,and SUVmax was 13.5.The average SUVmax of renal lesions in 7 patients was 13.34±6.93.There was no significant difference between diffuse infiltration and nodular infiltration(Z=-0.354,P=0.724).Conclusion:The renal infiltration of T-lymphoblastic lymphoma is characterized by the increase of both renal volume and the diffuse increase of FDG uptake.

关 键 词：T淋巴母细胞淋巴瘤 肾脏 淋巴瘤 继发性 体层摄影术 发射型计算机 X线计算机 脱氧葡萄糖 

分 类 号：R733.4[医药卫生—肿瘤]