即刻种植修复与延期种植修复对上颌单前牙患者牙周组织健康、美学效果以及炎症因子的影响  

The Effect of Immediate Implant and Delayed Implant Restoration on Periodontal Tissue Health,Aesthetic Effect and Inflammatory Factors in Patients with Maxillary Single Anterior Teeth

作　　者：张璐 冯艳芬 张瑞平 白青心 任琼 ZHANG Lu;FENG Yan-fen;ZHANG Rui-ping;BAI Qing-xin;REN Qiong(Department of Stomatology,The Fourth Medical Center of General Hospital of Chinese People's Liberation Army,Beijing,100089,China;Department of Prosthodontics,Oral Branch of Cangzhou People's Hospital,Cangzhou,Hebei,061000,China;Department of Stomatology,Ordos Central Hospital of Inner Mongolia,Ordos,Inner Mongolia,071000,China;Department of Stomatology,Xiamen Changgeng Hospital,Xiamen,Fujian,361028,China;Department of Stomatology,Henan Electric Power Hospital,Zhengzhou,Henan,450000,China)

机构地区：[1]中国人民解放军总医院第四医学中心口腔科,北京100089 [2]沧州市人民医院口腔分院修复科,河北沧州061000 [3]内蒙古鄂尔多斯市中心医院口腔科,内蒙古鄂尔多斯071000 [4]厦门长庚医院口腔科,福建厦门361028 [5]河南电力医院口腔科,河南郑州450000

出　　处：《现代生物医学进展》2021年第11期2061-2064,2132,共5页Progress in Modern Biomedicine

基　　金：北京市自然科学基金项目(7202181)。

摘　　要：目的:探讨即刻种植修复与延期种植修复对上颌单前牙患者牙周组织健康、美学效果以及炎症因子的影响。方法:回顾性分析2017年3月~2018年12月期间收治的80例上颌单前牙患者的临床资料,根据种植修复方式的不同分为A组(n=40,延期种植修复)和B组(n=40,即刻种植修复),比较两组患者植牙成功率、牙周组织健康、美学效果、炎症因子及并发症。结果:两组植牙成功率比较无差异(P>0.05)。两组修复后1个月、3个月、6个月、12个月牙周袋深度依次降低(P<0.05);B组修复后1个月、3个月、6个月、12个月牙周袋深度均低于A组(P<0.05)。两组修复后1个月、3个月、6个月、12个月红色美学指数(PES)评分依次升高(P<0.05);B组修复后1个月、3个月、6个月、12个月PES评分均高于A组(P<0.05)。两组修复前、修复后7 d、修复后30 d血清肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)水平均呈升高后降低趋势,B组修复后7 d、修复后30 d血清TNF-α、CRP水平均低于A组(P<0.05)。两组均未见严重并发症发生。结论:与延期种植修复相比,即刻种植修复治疗上颌单前牙患者对其牙周组织健康改善效果更佳,且炎症反应更轻微,美学效果更好,疗效显著且安全性好。Objective:To investigate the effects of immediate and delayed implant restoration on periodontal tissue health,aesthetic effect and inflammatory factors in patients with maxillary single anterior teeth.Methods:The clinical data of 80 patients with maxillary single anterior teeth from March 2017 to December 2018 were retrospectively selected,and patients were divided into group A(n=40,delayed implant restoration)and group B(n=40,immediate implant restoration)according to the different ways of implant restoration.The success rate of dental implant,periodontal tissue health,aesthetic effect,inflammatory factors and complications were compared between the two groups.Results:There was no significant difference in success rate of dental implant between the two groups(P>0.05).The periodontal pocket depth decreased successively at 1 month,3 months,6 months and 12 months after restoration in the two groups(P<0.05).The periodontal pocket depth in group B at 1 month,3 months,6 months and 12 months after restoration were lower than that in group A(P<0.05).The scores of red aesthetic index(PES)in the two groups increased successively at 1 month,3 months,6 months and 12 months after restoration(P<0.05).The scores of PES in group B were higher than those in group A at at 1 month,3 months,6 months and 12 months after restoration(P<0.05).The levels of serum tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)in the two groups showed an increasing and decreasing trend before,7 d after and 30 d after restoration.The levels of serum TNF-αand CRP in group B were lower than those in group A at 7 d and 30 d after restoration(P<0.05).There was no significant complication in both groups.Conclusion:Compared with delayed implant restoration,immediate implant restoration has a better effect on the periodontal tissue health in patients with single maxillary anterior teeth,with less inflammatory reaction,better aesthetic effect,significant curative effect and good security.

关 键 词：即刻种植修复 延期种植修复 上颌单前牙 牙周组织健康 美学效果 炎症因子 

分 类 号：R783[医药卫生—口腔医学]