内镜下黏膜剥离术治疗早期胃癌的疗效分析  

Efficacy analysis of endoscopic mucosal dissection in the treatment of early gastric cancer

作　　者：蔡永国[1] 陈彦磊 董堃博 白笠 CAI Yong-guo;CHEN Yan-lei;DONG Kun-bo(Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army,Yantai 264002,China)

机构地区：[1]中国人民解放军联勤保障部队第九七○医院,264002

出　　处：《中国实用医药》2021年第18期45-48,共4页China Practical Medicine

摘　　要：目的分析内镜下黏膜剥离术治疗早期胃癌的临床疗效。方法60例早期胃癌患者,随机分为观察组及对照组,各30例。观察组采用内镜下黏膜剥离术进行治疗,对照组采用常规外科肿瘤切除术进行治疗。比较两组患者的肿瘤切除率、术后并发症发生情况、手术时间及住院时间、术后复发率及生存率。结果两组患者的肿瘤均达到完全切除,切除率均为100.00%。观察组患者的术后并发症发生率3.33%低于对照组的20.00%,差异有统计学意义(P<0.05)。两组患者均未出现其他严重并发症。观察组患者的手术时间为(0.87±0.18)h,住院时间为(4.25±0.28)d,均短于对照组的(1.14±0.37)h、(6.69±0.97)d,差异有统计学意义(P<0.05)。两组患者术后2个月、6个月、1年、2年经胃镜及胸、腹部CT检查均无局部复发及远处转移情况发生。随防2年发现,观察组患者的生存率为96.67%(29/30),与对照组的93.33%(28/30)比较,差异无统计学意义(P>0.05)。结论内镜下黏膜剥离术治疗早期胃癌的临床疗效显著,可有效减少术后并发症发生率,促进患者尽早恢复,值得临床推广应用。Objective To analyze the clinical efficacy of endoscopic mucosal dissection in the treatment of early gastric cancer.Methods A total of 60 patients with early gastric cancer were randomly divided into observation group and control group,with 30 cases in each group.The observation group was treated with endoscopic mucosal dissection,and the control group was treated with conventional surgical tumor resection.The tumor resection rate,occurrence of postoperative complications,operation time and hospitalization time,postoperative recurrence rate and survival rate were compared between the two groups.Results The tumors of both groups were completely resected,and the resection rate was 100.00%.The incidence of postoperative complications 3.33%of the observation group was lower than 20.00%of the control group,and the difference was statistically significant(P<0.05).There were no other serious complications in the two groups.The operation time(0.87±0.18)h and hospitalization time(4.25±0.28)d of the observation group were shorter than(1.14±0.37)h and(6.69±0.97)d of the control group,and the difference was statistically significant(P<0.05).There were no local recurrences and distant metastases in the two groups after 2 months,6 months,1 year,and 2 years after operation by gastroscopy and CT examination of chest and abdomen.After 2 years of follow-up,the survival rate of the observation group was 96.67%(29/30),which had no statistically significant difference compared with 93.33%(28/30)of the control group(P>0.05).Conclusion Endoscopic mucosal dissection has remarkable clinical efficacy on early gastric cancer,and it can effectively lower the incidence of postoperative complications and promote the early recovery of patients,which is worthy of clinical promotion and application.

关 键 词：内镜下黏膜剥离术 早期胃癌 疗效 

分 类 号：R735.2[医药卫生—肿瘤]