Papular acantholytic dyskeratosis of the anogenital area with novel ATP2C1 gene mutations  

作　　者：Xue-Min Xiao Yi-Qun Jiang Wei Tian Cheng-Rang Li 

机构地区：[1]Department of Dermatology,The Union Hospital,Fujian Medical University,Fuzhou,Fujian 350001,China [2]Institute of Dermatology,Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and Sexually Transmitted Infections,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing,Jiangsu 210042,China

出　　处：《Chinese Medical Journal》2021年第12期1508-1510,共3页中华医学杂志（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.81602785 and 81472872);the Natural Science Foundation of Fujian,China(No.2017J05128);Fujian Provincial Health Technology Project(No.2019-ZQN-47);the Opening Foundation of Research Platform of Fujian University of Traditional Chinese Medicine(No.X2018018-Platform).

摘　　要：To the Editor:Focal acantholytic dyskeratosis(FAD)is used to describe a group of diseases with diverse clinical manifestations but characteristic histological structures.In 1984,the first case of“papular acantholytic dyskeratosis(PAD)of the vulvocrural area”was reported in a 23-year-old female with pathological manifestations of FAD and the researchers believed that it might be a new independent disease.[1]Recently,the relationship between PAD and Hailey-Hailey disease(HHD)as well as Darier disease(DD)is receiving increasing attention from scholars.We performed gene mutation screening in two patients with sporadic PAD and explored the nature of PAD.

关 键 词：DISEASES kerato SIS 

分 类 号：R75[医药卫生—皮肤病学与性病学]