光学体表追踪技术适用于儿童肿瘤精准放射治疗  

Application of OSMS in radiotherapy of children's tumors

作　　者：周略 李子煌 李壮玲 邓小年 吕得刚 李先明 唐娜 ZHOU Lue;LI Zihuang;LI Zhuangling;DENG Xiaonian;LV Degang;LI Xianming;TANG Na(Department of Oncology Radiotherapy,First Affiliated Hospital of Southern University of Science and Technology(Shenzhen People's Hospital),Shenzhen 518020,China;Department of Oncology Radiotherapy,Second Clinical College of Jinan University(Shenzhen People's Hospital),Shenzhen 518020,China;Department of Pathology,First Affiliated Hospital of Southern University of Science and Technology(Shenzhen People's Hospital),Shenzhen 518020,China;Department of Pathology,Second Clinical College of Jinan University(Shenzhen People's Hospital),Shenzhen 518020,China)

机构地区：[1]南方科技大学第一附属医院(深圳市人民医院)肿瘤放疗科,广东深圳518020 [2]暨南大学第二临床医学院(深圳市人民医院)肿瘤放疗科,广东深圳518020 [3]南方科技大学第一附属医院(深圳市人民医院)病理科,广东深圳518020 [4]暨南大学第二临床医学院(深圳市人民医院)病理科,广东深圳518020

出　　处：《分子影像学杂志》2021年第3期478-481,共4页Journal of Molecular Imaging

基　　金：国家自然科学基金青年科学基金(81702359);深圳市科技计划项目(JCYJ20180301170035531)。

摘　　要：目的探讨光学体表追踪技术(OSMS)在儿童肿瘤精准放射治疗中的摆位精度及其应用价值。方法选取6例儿童肿瘤患者,应用体表标记、激光灯配合OSMS协助摆位,每次摆位后治疗前进行锥形束CT(CBCT)扫描。分别记录OSMS及CBCT的左右、头脚、上下方向移动的误差。分析两组摆位误差关系,应用Bland-Altman法评估两种系统的一致性。治疗期间利用OSMS监测患者体位变化。结果CBCT与OSMS的左右、头脚、上下方向的移动误差分别是:0.207±0.076 cm,0.207±0.073 cm;0.186±0.072 cm,0.183±0.069 cm;0.206±0.068 cm,0.198±0.071 cm,差异均无统计学意义(P>0.05)。在CBCT与OSMS的左右、头脚、上下方向的移动差值分别有4.65%(6/129)、5.43%(7/129)、3.88%(5/129)在95%LoA之外,在其一致性范围内,差值的绝对值最大分别为0.06、0.09、0.11 cm。结论OSMS是一种高精度、高效的图像引导方式,能精准地减少摆位误差,提高摆位的效率,适合于儿童肿瘤的精准放疗。Objective To explore the positioning accuracy and application value of optical body surface tracking technology(OSMS)in precision radiotherapy for children's tumors.Methods Six pediatric tumor patients were included.The body surface marking,laser light and optical surface tracking technology(OSMS)were applied to verified the patients pretreatment position,and perform CBCT scan before treatment after each positioning.The error of the left and right,head and foot,up and down directions of OSMS and CBCT were record.Theχ^(2) test was used to compare the two groups to analyze the set-up error relationship between the two groups,and the Bland-Altman method was used to evaluate the consistency of the two systems.During treatment,the patient's posture changes were observed by OSMS monitors.Results The movement errors of CBCT and OSMS in the left and right,head and foot,and up and down directions were:0.207±0.076 cm,0.207±0.073 cm;0.186±0.072 cm,0.183±0.069 cm;0.206±0.068 cm,0.198±0.071 cm,which had no significant difference(P>0.05).There were 4.65%(6/129),5.43%(7/129),3.88%(5/129)of movement differences between CBCT and OSMS in the left and right,head and foot,up and down directions Outside of 95%LoA.In the consistency range,the maximum absolute values of the differences were 0.06,0.09,0.11 cm,respectively.Conclusion OSMS is a high-precision and high-efficiency image guidance method,which can accurately reduce positioning errors and improve positioning efficiency.It is suitable for precise radiotherapy of childhood tumors.

关 键 词：儿童肿瘤 图像引导放疗 光学体表追踪技术 锥形束CT 摆位误差 

分 类 号：R730.55[医药卫生—肿瘤]