胰腺癌的风险因素、早期诊断和治疗方案研究进展  

Review of Risk Factors,Early Diagnosis and Treatment for Pancreatic Cancer

作　　者：姚黎超 武伦 王伟[1] 叶林 汤志刚[1] YAO Lichao;WU Lun;WANG Wei;YE Lin;TANG Zhigang(Department of Pancreatic Surgery,Renmin Hospital of Wuhan University,Wuhan,Hubei,430060,China)

机构地区：[1]武汉大学人民医院胰腺外科,湖北武汉430060

出　　处：《肿瘤药学》2021年第3期284-288,共5页Anti-Tumor Pharmacy

基　　金：国家自然科学基金面上项目(81272740)。

摘　　要：胰腺癌是一种预后极差的疾病,近年来其发病率不断上升,许多患者确诊时已处于晚期,无法行根治性切除术,其预后在所有肿瘤中排名最末。随着新的外科技术和医学疗法的引入,以及不断发展的胰腺癌综合管理理念,胰腺癌患者的预后得到了适度改善,但5年生存率并未显著提高。因此,更好地了解与胰腺癌相关的风险因素,确定早期检测生物标志物,提高早期诊断率至关重要。本综述旨在概述胰腺癌风险因素、早期诊断和治疗方案的最新进展。Pancreatic cancer is a disease with awfully poor prognosis,and its incidence has been increasing in recent years.Many patients are diagnosed with advanced cancer,and few patients can undergo radical resection,ranking last among all cancer patients in terms of prognosis.With the introduction of new surgical techniques and medical therapies,and the constantly developing concept of integrated management of pancreatic cancer,the prognosis of pancreatic cancer patients has achieved some improvement.However,the 5-year survival rate has not been improved.Therefore,it is crucial to better understand the pancreatic cancer-related risk factors,identify early detection biomarkers,and improve early diagnosis rate.This review aims to summarize the latest researches of risk factors,early diagnosis and treatment options for pancreatic cancer.

关 键 词：胰腺癌 风险因素 早期诊断 临床治疗 

分 类 号：R735.9[医药卫生—肿瘤]