局部微波消融联合髋臼球囊扩张骨水泥成形术治疗晚期髋臼转移瘤的临床疗效  

Clinical efficacy of local microwave ablation combined with percutaneous kyphoplasty in the treatment of advanced acetabular metastases

作　　者：刘斌[1] 杨芳[2] 林翔[1] 袁振超[1] LIU Bin;YANG Fang;LIN Xiang;YUAN Zhenchao(Department of Bone and Soft Tissue,Guangxi Medical University Cancer Hospital,Nanning 530021,China;Department of Medical Record,Guangxi Medical University Cancer Hospital,Nanning 530021,China)

机构地区：[1]广西医科大学附属肿瘤医院骨软组织外科,南宁530021 [2]广西医科大学附属肿瘤医院病案室,南宁530021

出　　处：《中国癌症防治杂志》2021年第3期301-304,共4页CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT

基　　金：广西医疗卫生适宜技术开发与推广应用项目(S2020101,S2019042);广西壮族自治区中医药管理局自筹经费科研课题(GZZC2020231);广西卫生健康委员会自筹经费科研课题(Z20190153)。

摘　　要：目的比较局部微波消融联合髋臼球囊扩张骨水泥成形术与传统髋臼球囊扩张骨水泥成形术治疗晚期髋臼转移瘤的临床疗效。方法选取2015年12月至2020年1月就诊于广西医科大学附属肿瘤医院的晚期髋臼转移瘤的患者32例,患者行局部微波消融联合髋臼球囊扩张骨水泥成形术(观察组)或传统髋臼球囊扩张骨水泥成形手术治疗(对照组)。通过手术时间、术中出血量、疼痛视觉模拟评分(VAS)、术后并发症等,比较两种治疗手段的疗效。结果两组患者手术时间、术中出血量、术后卧床时间、术前VAS评分及变化等差异均无统计学意义(P>0.05)。观察组与对照组相比,术后VAS评分降低[(3.43±0.50)分vs(4.87±0.44)分,P=0.042],术后并发症总发生率(18.8%vs 75.0%,P<0.001)和术后复发率(6.3%vs 43.7%,P=0.040)也均低于对照组。结论局部微波消融联合髋臼球囊扩张骨水泥成形术治疗晚期髋臼转移瘤,术后疼痛减轻,复发率降低,是晚期髋臼转移瘤一种安全有效的微创治疗手段。Objective To compare the clinical efficacy of local microwave ablation combined with percutaneous kyphoplasty and conventional percutaneous kyphoplasty in the treatment of advanced acetabular metastases.Methods A total of 32 patients with advanced acetabular metastases received treatment in Guangxi Medical University Cancer Hospital from December 2015 to January 2020 were selected,and divided into local microwave ablation combined with percutaneous kyphoplasty group(observation group)and percutaneous kyphoplasty group(control group).The differences between two treatment methods were compared based on operation time,intraoperative bleeding loss,visual analogue scale(VAS)of pain and postoperative complications.Results No significant differences were found in operative time,intraoperative blood loss,postoperative bed rest,preoperative VAS scores and changes between the two groups(P>0.05).Compared with the control group,the postoperative VAS score in the observation group was reduced[(3.43±0.50)scores vs(4.87±0.44)scores,P=0.042].The overall incidence of postoperative complications(18.8%vs 75.0%,P<0.001)and the postoperative recurrence rate(6.3%vs 43.7%,P=0.04)were lower than those in the control group.Conclusions Local microwave ablation combined with percutaneous kyphoplasty in the treatment of advanced acetabular metastatic tumors can reduce postoperative pain and recurrence rate.It is a safe and effective minimally-invasive treatment for advanced acetabular metastases.

关 键 词：微波消融 骨水泥 髋臼转移瘤 临床疗效 

分 类 号：R738.1[医药卫生—肿瘤]