促甲状腺激素型垂体腺瘤伴蛋壳样钙化1例报告及文献复习  

stimulating hormone type pituitary adenoma with eggshell calcification:a case report and literature review

作　　者：马龙涛 梅加明 牛朝诗 Ma Longtao;Mei Jiaming;Niu Chaoshi(Department of Neurosurgery,the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,230001,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)神经外科 [2]脑功能与脑疾病安徽省重点实验室,安徽省神经系统疾病(神经外科)临床研究中心

出　　处：《立体定向和功能性神经外科杂志》2021年第1期9-12,共4页Chinese Journal of Stereotactic and Functional Neurosurgery

基　　金：中央引导地方科技创新专项项目(编号:2019b07030001)。

摘　　要：目的加深对影像学表现为伴有蛋壳样钙化垂体瘤的认识,提高对鞍区占位灶的鉴别诊断能力。方法回顾分析就诊我科的1例影像学表现为蛋壳样钙化的促甲状腺激素型垂体腺瘤患者的临床影像学资料,并复习相关文献。结果该患者头颅CT检查发现鞍区蛋壳样钙化灶,考虑鞍区占位行手术治疗,术后病理提示促甲状腺激素型垂体瘤,免疫组化提示TSH(+),术后随访13个月,未见肿瘤复发,视力视野正常,激素水平均在正常范围内。结论临床上伴有钙化的鞍区占位病变除了常见的颅咽管瘤和脑膜瘤等,还需考虑垂体腺瘤的可能,术前仔细阅片,结合血清激素水平和临床表现有助于术前诊断,指导进一步手术治疗,选择合适的手术方式,使患者受益最大化。Objective In order to deepen the understanding of pituitary adenoma with eggshell calcification on imaging and improve the ability of differential diagnosis of sellar space occupying lesions.Methods The clinical imaging data of a patient with thyroid stimulating hormone pituitary adenoma with eggshell calcification were retrospectively analyzed,and the related literature was reviewed.Results The patient’s skull CT examination found eggshell like calcification in sellar region,and the sellar region was considered for surgical treatment.Postoperative pathology showed thyrotropin pituitary tumor,and immunohistochemistry showed TSH(+).After 13 months of follow-up,no tumor recurrence,normal vision and visual field,and hormone levels were within the normal range.Conclusion In addition to the common craniopharyngioma and meningioma,the possibility of pituitary adenoma should also be considered for the sellar space occupying lesions with calcification.Careful preoperative film reading,combined with serum hormone levels and clinical manifestations are helpful for preoperative diagnosis,guiding further surgical treatment,selecting appropriate surgical methods,and maximizing the benefits of patients.

关 键 词：鞍区占位 颅内钙化灶 促甲状腺激素型垂体瘤Thyroid 

分 类 号：R736.4[医药卫生—肿瘤]