经外周静脉置入中心静脉导管与植入式静脉输液港在乳腺癌化疗中的应用  

Application of peripherally inserted central catheter and implantable venous access port through peripheral vein in breast cancer chemotherapy

作　　者：朱峰微[1] 柳春波[1] 苏文敏[1] 章立楠[1] ZHU Feng-Wei;LIU Chun-Bo;SU Wen-Min(Affiliated Hospital of Medical School,Ningbo University,Ningbo,Zhejiang 315020,China)

机构地区：[1]宁波大学医学院附属医院,浙江宁波315020

出　　处：《中国妇幼保健》2021年第12期2889-2891,共3页Maternal and Child Health Care of China

基　　金：浙江省医药卫生科技计划项目(2020KY873)。

摘　　要：目的比较经外周静脉置入中心静脉导管(PICC)与植入式静脉输液港(IVAP)在乳腺癌化疗中的应用效果。方法选取2018年1月-2019年10月宁波大学医学院附属医院收治的124例乳腺癌化疗患者为研究对象,随机分为观察组和对照组,每组各62例,观察组患者采用IVAP置管,对照组患者采用PICC置管。比较两组患者置管相关指标及术后并发症发生情况,置管后3个月采用欧洲癌症研究及治疗组织的生活质量量表(QLQ-C30)评价患者的生活质量。结果两组患者一次置管成功率比较,差异无统计学意义(P>0.05)。观察组患者置管操作时间明显长于对照组,差异有统计学意义(P<0.05)。观察组患者导管留置时间明显长于对照组,并发症发生率明显低于对照组,差异均有统计学意义(均P<0.05)。观察组患者QLQ-C30量表各维度评分均明显高于对照组,差异均有统计学意义(均P<0.05)。结论PICC与IVAP均是乳腺癌化疗患者有效的长期深静脉通道,但是IVAP在导管留置时间、并发症发生率及患者生活质量方面均明显优于PICC。Objective To compare the effect of peripherally inserted central catheters(PICC)and implantable venous access port(IVAP)in breast cancer chemotherapy.Methods A total of 124 patients with breast cancer treated by chemotherapy in the Affiliated Hospital of Medical School,Ningbo University,from January 2018 to October 2019 were selected as the research subjects and randomly divided into observation group and control group,with 62 patients in each group.Patients in the observation group received IVAP,and patients in the control group received PICC.The indicators related to catheterization and the incidence of postoperative complications were compared between the two groups.Three months after catheterization,the quality of life of the patients was evaluated by the European Organization for Research and Treatment of Cancer Quality of Life Scale(QLQ-C30).Results There was no significant difference in the success rate of one-time catheterization between the two groups(P>0.05).The operation time of observation group was significantly longer than control group,and the difference was statistically significant(P<0.05).The catheter indwalling time in observation group was significantly longer than that in control group,and the incidence of complications was significantly lower than that in control group,the differences were statistically significant(all P<0.05).The scores of each dimension of QLQ-C30 scale in observation group were significantly higher than those in control group,and the differences were statistically significant(all P<0.05).Conclusion PICC and IVAP were effective long-term deep vein access for breast cancer patients undergoing chemotherapy,but IVAP is significantly better than PICC in catheter indwelling time,complication rate and patients’quality of life.

关 键 词：乳腺癌 化疗 植入式静脉输液港 经外周静脉置入中心静脉导管 生活质量 

分 类 号：R737.9[医药卫生—肿瘤]