Drug-drug cocrystals:Opportunities and challenges  

作　　者：Xiaojuan Wang Shuzhang Du Rui Zhang Xuedong Jia Ting Yang Xiaojian Zhang 

机构地区：[1]Department of Phamacy,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China

出　　处：《Asian Journal of Pharmaceutical Sciences》2021年第3期307-317,共11页亚洲药物制剂科学（英文）

摘　　要：Recently,drug-drug cocrystal attracts more and more attention.It offers a low risk,low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable therapeutically effective component without any chemical modification.Having so many advantages,to date,the reported drug-drug cocrystals are rare.Here we review the drug-drug cocrystals that reported in last decade and shed light on the opportunities and challenges for the development of drug-drug cocrystals.

关 键 词：Drug-drug cocrystal Drug combination COCRYSTAL Physicochemical property 

分 类 号：R917[医药卫生—药物分析学]