On improving strigolactone mimics for induction of suicidal germination of the root parasitic plant Striga hermonthica  

作　　者：Ikuo Takahashi Kosuke Fukui Tadao Asami 

机构地区：[1]Graduate School of Agricultural and Life Sciences,The University of Tokyo,Tokyo 113-8657,Japan

出　　处：《aBIOTECH》2021年第1期1-13,共13页生物技术通报（英文版）

基　　金：partly supported by a grant from the Core Research for Evolutional Science and Technology(CREST)Program of the Japan Science and Technology Agency(JST);the Japan International Cooperation Agency(JICA);JST under a joint program of Science and Technology Research Partnership for Sustainable Development(SATREPS);a JSPS Grant-in-Aid for Scientific Research(Grant no.18H03939 to TA).

摘　　要：Strigolactones(SLs)are plant hormones that regulate the branching of plants and seed germination stimulants of root parasitic plants.As root parasites are a great threat to agricultural production,the use of SL agonists could be anticipated to provide an efficient method for regulating root parasites as suicidal germination inducers.A series of phenoxyfuranone-type SL mimics,termed debranones,has been reported to show potent bioactivities,including reduction of the tiller number on rice,and stimulation of seed germination in the root parasite Striga hermonthica.To exert both activities,two substituents on the phenyl ring of the molecules were important but at least a substituent at the 2-position must be an electron-withdrawing group.However,little is known about the effect of the properties of the substituents at the 2-position on bioactivities.Here,we found that different substituents at the 2-position give different preferences for bioactivities.Halogenated debranones were more effective than the others and SL agonist GR24 for inhibiting rice tiller but far less effective in the induction of S.hermonthica germination.Meanwhile,nitrile and methyl derivatives clearly stimulated the germination of S.hermonthica seeds.Although their IC_(50) values were 100 times higher than that of GR24 in the receptor competitive binding assay,their physiological activities were approximately 1/10 of GR24.These differences could be due to their uptake in plants and/or their physicochemical stability under our experimental conditions.These findings could support the design of more potent and selective SL agonists that could contribute to solving big agricultural issues.

关 键 词：AGONIST Rice Root parasitic weed Seed germination STRIGOLACTONE TILLERING 

分 类 号：Q94[生物学—植物学]