机构地区:[1]江西省萍乡市人民医院神经外科,江西萍乡337000
出 处:《中国当代医药》2021年第19期96-98,102,共4页China Modern Medicine
基 金:江西省卫生健康委科技计划项目(20204416)。
摘 要:目的探讨3D导板在高血压性脑出血(HICH)软通道微创穿刺抽吸引流术中应用效果。方法选取2019年1月—2020年9月萍乡市人民医院收治的40例HICH患者作为研究对象,采用随机数字表法将其分为对照组(n=20)和观察组(n=20)。对照组采用立体定向软通道穿刺引流术治疗,观察组采用3D导板软通道穿刺引流术治疗,随访至术后8周。比较两组术前及术后8周的神经功能缺损程度及血清神经元特异性烯醇化酶(NSE)、中枢神经特异蛋白(S100-β)水平,统计两组术后颅内感染的发生情况。结果术前,两组美国国立卫生研究院卒中量表(NIHSS)评分比较,差异无统计学意义(P>0.05);术后8周,两组NIHSS评分均低于术前,且观察组NIHSS评分低于对照组,差异有统计学意义(P<0.05);术前,两组血清NSE、S100-β水平比较,差异无统计学意义(P>0.05);术后8周,两组血清NSE、S100-β水平均低于术前,且观察组血清NSE、S100-β水平低于对照组,差异有统计学意义(P<0.05);两组颅内感染发生率比较,差异无统计学意义(χ2=1.026,P=0.311)。结论3D导板在HICH软通道微创穿刺抽吸引流术中的应用效果较好,可有效降低神经功能缺损程度,改善患者神经功能,且不会增加并发症的发生风险。Objective To investigate the application effect of 3D guide plate in minimally invasive soft channel puncture and drainage for hypertensive intracerebral hemorrhage(HICH).Methods A total of 40 patients with HICH treated in Pingxiang People's Hospital from January 2019 to September 2020 were selected as the research subjects according to the random number table method,they were divided into the control group(n=20)and the observation group(n=20).The control group was treated with stereotactic drainage,the observation group was treated with 3D guide plate soft channel puncture and drainage,the patients were followed up until 8 weeks after operation.The degree of neurological deficit,serum neuron specific enolase(NSE)and central neurological specific protein(S100-β)levels before and 8 weeks after operation were compared between the two groups,the occurrence of postoperative intracranial infection was counted between the two groups.Results Before operation,there was no statistical significant difference in the comparison of the National Institutes of Health Stroke Scale(NIHSS)scores of both groups(P>0.05);8 weeks after operation,the NIHSS scores of both groups were lower than those before operation,and the NIHSS score of the observation group was lower than that of the control group,there were statistical significant differences(P<0.05);before operation,there was no statistical significant difference in the comparison of serum NSE and S100-βlevels of both groups(P>0.05);8 weeks after operation,the serum NSE and S100-βlevels of both groups were lower than those before operation,and the serum NSE and S100-βlevels of the observation group were lower than those of the control group,the differences were statistically significant(P<0.05);there was no statistically significant difference in the incidence of postoperative intracranial infection between the two groups(χ2=1.026,P=0.311).Conclusion The application effect of 3D guide plate in HICH soft channel minimally invasive puncture and drainage is better,which can effe
关 键 词:高血压性脑出血 3D导板软通道穿刺引流术 立体定向软通道穿刺引流术 神经功能缺损
分 类 号:R74[医药卫生—神经病学与精神病学]
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