CT导向立体定向技术下经额入路立体定向技术治疗重症丘脑出血的临床效果  

Clinical effect of CT-guided stereotactic technique through frontal approach in the treatment of severe thalamic hemorrhage

作　　者：卢致金 汤涛[1] 肖艳平 曾繁云 LU Zhi-jin;TANG Tao;XIAO Yan-ping;ZENG Fan-yun(Trauma Emergency Center,Ganzhou People's Hospital,Jiangxi Province,Ganzhou341000,China)

机构地区：[1]江西省赣州市人民医院创伤急救中心,江西赣州341000

出　　处：《中国当代医药》2021年第19期110-112,共3页China Modern Medicine

基　　金：江西省赣州市指导性科技计划项目(GZ2020ZSF243)。

摘　　要：目的探讨CT导向立体定向技术下经额入路立体定向技术治疗重症丘脑出血的临床应用。方法选取2017年3月—2019年5月赣州市人民医院收治的81例重症丘脑出血患者作为研究对象,按照随机数字表法分为对照组(n=40)和治疗组(n=41)。对照组使用双侧脑室钻孔引流术;治疗组使用CT导向立体定向技术下经额入路立体定向技术指导下的脑钻孔引流术,两组患者均在术后观察2周。比较两组的临床疗效、临床相关指标、术后并发症、术前及术后3 d血清炎症因子水平。结果治疗组临床总有效率高于对照组,差异有统计学意义(P<0.05);治疗组患者的引流管留置、意识恢复及重症加强护理病房(ICU)住院时间均短于对照组,差异有统计学意义(P<0.05);治疗组术后并发症总发生率低于对照组,差异有统计学意义(P<0.05);术前,两组患者血清炎症因子水平比较,差异无统计学意义(P>0.05);术后3 d,治疗组血清肿瘤坏死因子(TNF)-α、C反应蛋白(CRP)、白细胞介素(IL)-6水平均低于对照组,差异有统计学意义(P<0.05)。结论CT导向立体定向技术下经额入路立体定向技术治疗重症丘脑出血患者能有效降低手术创伤,疗效更佳,减少术后并发症。Objective To explore the clinical application of stereotactic treatment of severe hemorrhage in the hypothalamus Discussion CT-guided stereotactic approach by the amount.Methods A total of 81 patients with severe thalamic hemorrhage admitted to Ganzhou People's Hospital from March 2017 to May 2019 were selected as the research object.According to the random number table method,they were divided into the control group(n=40)and the treatment group(n=41).The control group was treated with bilateral ventricle drilling and drainage;the treatment group was treated with CT-guided stereotactic technique to guide brain drilling and drainage under the guidance of transfrontal approach stereotactic technique,all patients were observed for 2 weeks after surgery.The clinical efficacy,clinical related indicators,postoperative complications,and serum inflammatory factor levels before and 3 days after operation were compared between the two groups.Results The total clinical effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).The indwelling drainage tube,recovery of consciousness and Intensive Care Unit(ICU)stay in the treatment group were shorter than those in the control group,the differences were statistically significant(P<0.05).The total postoperative complication rate in the treatment group was lower than that of the control group,the differences were statistically significant(P<0.05).Before surgery,there were no significant differences in serum inflammatory factor levels between the two groups(P>0.05);3 days after surgery,serum tumor necrosis factor(TNF)-α,C-reactive protein(CRP),interleukin(IL)-6 levels in the treatment group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion CT-guided stereotactic technology through the frontal approach stereotactic technology in the treatment of patients with severe thalamic hemorrhage can effectively reduce surgical trauma,with better curat

关 键 词：丘脑出血 CT导向立体定向 脑钻孔引流术 炎症因子 并发症 

分 类 号：R74[医药卫生—神经病学与精神病学]