Cyclopeptides from Amanita exitialis  

作　　者：Jing-Hua XUE Ping WU Yu-Lang CHI Liang-Xiong XU and Xiao-Yi WEI 

机构地区：[1]Key Laboratory of Plant Resources Conservation and Sustainable Utilization,South China Botanical Garden,Chinese Academy of Sciences,Xingke Road 723,Tianhe District,Guangzhou 510650,China

出　　处：《Natural Products and Bioprospecting》2011年第1期52-56,共5页应用天然产物（英文）

基　　金：This work was supported by the Knowledge Innovation Program of the Chinese Academy of Sciences(No.KSCX2-YW-N-036).

摘　　要：A new cyclic nonapeptide, amanexitide (1), along with the known cyclopeptides, a- and b-amanitins, was isolated from the fruiting bodies of Amanita exitialis, a newly described poisonous mushroom endemic to Guangzhou, Guangdong Province, China. Its amino acid composition and absolute configuration were determined by chemical degradation and derivatization followed by chiral GC analysis. Its amino acid sequence was elucidated by extensive analysis of ESIMS/MS and FTICRMS data. The occurrence of 1 in this mushroom is interesting because it has a structure closely related to antamanide, a cyclic decapeptide with antidote activity against amatoxins and phallotoxins, occurring in A. phalloides.

关 键 词：AMANITA Amanita exitialis CYCLOPEPTIDES amanexitide 

分 类 号：F42[经济管理—产业经济]