supported by the Shanxi Provincial Key Research and Development Project(202102130501004).
TAG-assisted peptide synthesis technology enables optimal conservation of Fmoc amino acid raw materials and chemical solvents while eliminating the need for intricate chromatographic purification processes.This work p...
supported financially by the grants(nos.21532007 and 21772213)from the National Natural Science Foundation of the People’s Republic of China.
Four unprecedented macrocyclic nonapeptides,orberryamides A–D(1–4),were isolated from Glycosmis pentaphylla(orangeberry)and structurally characterized by obtaining solid data from numerous analytical measurements.Co...
BACKGROUND: Evolutionary novelties, be they morphological or biochemical, fascinate both scientists and non-scientists alike. These types of adaptations can significantly impact the biodiversity of the organisms in w...
financially supported by the National Natural Science Foundation of China(Nos.81322051 and 31400300);the Natural Science Foundation of Jiangsu Province(No.BK20151442);the Project Funded by the Priority Academic Program Development(PAPD) of Jiangsu Higher Education Institutions
Two cyclopeptides, celogentin L(1) and its epimer lyciumin A(2) were firstly isolated from Celosia argentea L.. The planar structures of the two compounds were fully determined by spectroscopic data, including 1 D-, 2...
the Program for Jiangsu Province Innovative Research Team,the National Basic Research Program of China(2013CB127505);the National Natural Science Foundation of China(31470428);the Project of State Key Laboratory of Natural Medicines(SKLNMZZCX201614);the Foundation of High-level Talent Introduction of China Pharmaceutical University.We are grateful to Prof.Yu-Min Shui(Kunming Institute of Botany,CAS)for identification of the material.
Two new cyclic nonapeptides,named clausenlanins A(1)and B(2),were isolated from the roots and rhizomes of Clausena lansium.Their structures were elucidated as cyclo-(Gly^(1)-L-Leu^(2)-L-Ile^(3)-L-Leu^(4)-L-Leu^(5)-L-L...
Two new cyclopeptides, nagitides A and B, were isolated from the stem bark ofPodoearpus nagi. Their struc- tures were elucidated on the basis of NMR experiments including IH-IH COSY, HSQC, HMBC, ROESY, etc. This is th...
An increasing number of cyclopeptides have been discovered as products of ribosomal synthetic pathway. The biosynthetic study of these cyclopeptides has revealed interesting new mechanisms for cyclization. This review...
This work was supported by the Knowledge Innovation Program of the Chinese Academy of Sciences(No.KSCX2-YW-N-036).
A new cyclic nonapeptide, amanexitide (1), along with the known cyclopeptides, a- and b-amanitins, was isolated from the fruiting bodies of Amanita exitialis, a newly described poisonous mushroom endemic to Guangzhou,...
New minor cyclic peptides, named arenariphilin C 1 and arenariphilin D 2, were isolated from the whole plants of Arenaria oreophila (Caryophyllaceae). Their structures were determined as cyclo(Pro^1-Pro2-Leu^1-Leu2...