Clausenlanins A and B,Two Leucine-Rich Cyclic Nonapeptides from Clausena lansium  

作　　者：Shai-Ping Hu Wei-Wu Song Si-Meng Zhao Ning-Hua Tan 

机构地区：[1]School of Traditional Chinese Pharmacy and State Key Laboratory of Natural Medicines,China Pharmaceutical University,Nanjing 211198,Jiangsu,People’s Republic of China [2]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,Yunnan,People’s Republic of China [3]School of Chemistry&Chemical Engineeing,Zhoukou Normal University,Zhoukou 466001,Henan,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2017年第4期307-313,共7页应用天然产物（英文）

基　　金：the Program for Jiangsu Province Innovative Research Team,the National Basic Research Program of China(2013CB127505);the National Natural Science Foundation of China(31470428);the Project of State Key Laboratory of Natural Medicines(SKLNMZZCX201614);the Foundation of High-level Talent Introduction of China Pharmaceutical University.We are grateful to Prof.Yu-Min Shui(Kunming Institute of Botany,CAS)for identification of the material.

摘　　要：Two new cyclic nonapeptides,named clausenlanins A(1)and B(2),were isolated from the roots and rhizomes of Clausena lansium.Their structures were elucidated as cyclo-(Gly^(1)-L-Leu^(2)-L-Ile^(3)-L-Leu^(4)-L-Leu^(5)-L-Leu^(6)-L-Leu^(7)-L-Leu^(8)-L-Leu^(9))(1)and cyclo-(Gly^(1)-L-Leu^(2)-L-Val^(3)-L-Leu^(4)-L-Leu^(5)-L-Leu^(6)-L-Leu^(7)-L-Leu^(8)-L-Leu^(9))(2)respectively on the basis of extensive spectroscopic analysis,particularly 2D NMR spectra taken at the temperature of 338 or 303 K and MS.

关 键 词：Clausena lansium CYCLOPEPTIDES Clausenlanin A Clausenlanin B 

分 类 号：O62[理学—有机化学]