近距离放疗在食管癌治疗中的应用  

Application of brachytherapy in the treatment of esophageal cancer

作　　者：郭昕 韩东梅[1] 赵红福[1] 程光惠[1] Guo Xin;Han Dongmei;Zhao Hongfu;Cheng Guanghui(Department of Radiotherapy,China-Japan Union Hospital of Jilin University,Changchun 130033,China)

机构地区：[1]吉林大学中日联谊医院放射治疗科,长春130033

出　　处：《国际放射医学核医学杂志》2021年第4期257-263,共7页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：国家自然科学基金面上项目(82073331);吉林省科技厅项目(20190303151SF);吉林省卫生和计划生育委员会项目(2014ZC054);吉林省科技厅白求恩专项研究(20160101079JC);吉林大学横向课题(2015373、2019155)。

摘　　要：食管癌是一种常见的消化系统肿瘤,手术和放疗是其最主要的根治性治疗方案。放疗对各期食管癌均具有较好的疗效,其中,外照射放疗是主要方法,近距离放疗(BT)作为放疗的分支,对食管癌的治疗具有辅助作用。由于食管是人体的自然管腔,食管局部肿瘤可采用腔内BT进行治疗;复发转移病灶可采用组织间插植BT进行治疗。笔者从BT技术、施源器、靶区勾画以及剂量方案等方面对BT在食管癌治疗中的应用进行综述。Esophageal cancer is a common digestive system tumor.Surgery and radiotherapy are the most important radical treatment options for esophageal cancer.Radiotherapy has good curative effects for all stages of esophageal cancer,and external beam radiotherapy is the main method.Brachytherapy(BT),as a branch of radiotherapy,plays an auxiliary role in the treatment of esophageal cancer.Since the esophagus is the natural lumen of human body,intracavitary BT is used to treat local esophageal tumors;interstitial BT is used to treat recurrent metastatic lesions.This paper reviews the application of BT in the treatment of esophageal cancer from the aspects of technique,source applicator,target area delineation and dosage regimen.

关 键 词：食管肿瘤 近距离放射疗法 肿瘤治疗方案 

分 类 号：R735.1[医药卫生—肿瘤] R730.55[医药卫生—临床医学]