Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans  

作　　者：Rui Chu Luo-Sheng Wan Xing-Rong Peng Mu-Yuan Yu Zhi-Run Zhang Lin Zhou Zhong-Rong Li Ming-Hua Qiu 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China [2]University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Natural Products and Bioprospecting》2016年第4期217-223,共7页应用天然产物（英文）

基　　金：This work was supported financially by Programme of Key New Productions of Yunnan Province,Centre of CHINA(No.2015BB002);The STS Programme of Chinese Academy of Sciences(KFJ-SW-STS-143-8);as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2015-ZZ09).

摘　　要：Five new ent-kaurane diterpenoids,named mascaroside Ⅲ–Ⅴ(1–3),and 20-nor-cofaryloside Ⅰ–Ⅱ(4–5),together with seven known diterpenoids,were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee.Their chemical structures were elucidated by extensive spectroscopic analyses.Meanwhile,cytotoxicity assay against HL-60,A-549,SMMC-7721,MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity.

关 键 词：Coffea arabica L. Green coffee beans DITERPENOIDS Structural elucidation 

分 类 号：O62[理学—有机化学]