云南高校图书馆联盟文献共享服务平台- DITERPENOIDS

DITERPENOIDS: 作品数：159被引量：213H指数：6; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：皮晓雪杨蓉吴琼谢可辉付宏征更多>>; 相关机构：中国科学院北京大学扬州大学中国医学科学院中国协和医科大学更多>>; 相关期刊：《Progress in Natural Science:Materials International》《Petroleum Science》《Molecular Plant》《Chinese Journal of Chemistry》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金国家教育部博士点基金更多>>

Ent-pimarane and ent-kaurane diterpenoids from Siegesbeckia pubescens and their anti-endothelial damage effect in diabetic retinopathy: 《Chinese Journal of Natural Medicines》2025年第2期234-244,共11页Mengjia Liu Tingting Luo Rongxian Li Wenying Yin Fengying Yang Di Ge Na Liu; supported by the National Natural Science Foundation of China (No.82073728);the Natural Science Foundation of Shandong Province (No.ZR2021MH357)。; Diabetic retinopathy,a prevalent and vision-threatening microvascular complication of diabetes mellitus,is the leading cause of blindness among middle-aged and elderly individuals.Natural diterpenoids isolated from Si...; 关键词：Siegesbeckia pubescens Natural diterpenoid Diabetic retinopathy Oxidative stress Inflammatory response

Highly anticipated natural diterpenoids as an important source of new drugs in 2013-2023: 《Chinese Chemical Letters》2025年第1期119-136,共18页Yingjie Wang Peng Tang Wenchao Tu Qi Gao Cuizhu Wang Luying Tan Lixin Zhao Hongye Han Liefeng Ma Kouharu Otsuki Weilie Xiao Wenli Wang Jinping Liu Yong Li Zhajun Zhan Wei Li Xianli Zhou Ning Li; This review covers the structures of diterpenoids,including chain(72),monocyclic(9),labdane-type(67),clerodane-type(127)abietane-type(716),ent-kaurane-type(89),grayanane-type(331),ingenanetype(55),tigliane-type(154),d...; 关键词：Natural diterpenoids Structures BIOACTIVITIES Druggability Leading compounds New drugs

Skeleton Rearranged and Oxygenated ent-Rosane Diterpenoids with Antiadipogenic Activity from Euphorbia milii: 《Chinese Journal of Chemistry》2024年第24期3211-3218,共8页Qin-Qin Song Yue Guo Peng Sun Yao-Yue Fan Kai-Long Ji; Financial support from the National Natural Science Foundation of China(No.82122062);the 145 Programs(XTBG-145)of Xishuangbanna Tropical Botanical Garden,Chinese Academy of Sciences(CAS);the Program of CAS Key Laboratory of Tropical Plant Resources and Sustainable Use(No.20228012802)is highly acknowledged.; Five unreported and oxygenated ent-rosane diterpenoids(ent-RDs),Euphomillanols A—E(1—5),were isolated from Euphorbia milii.Among them,compounds 1 and 2 are unprecedented 7/7/6-fused tricyclic 5,10-seco-ent-RDs and p...; 关键词：ent-Rosane diterpenoids Euphorbia milii Structure elucidation Configuration determination Biosynthetic pathway hypothesis Oxidation Biological activity Antiadipogenic activity

Bioinspired Total Syntheses of Grayanotoxins II/III,Kalmanol,and Rhodomollacetals A–C with Three Distinct Skeletons: 《CCS Chemistry》2024年第11期2741-2748,共8页Hao Cheng Tianhao Ma Xiao Liu Yanxing Jia; supported by the National Natural Science Foundation(grant nos.22331001 and 21925101)。; Grayanane diterpenoids,which have intricate molecular architecture and interesting pharmacological properties,have attracted considerable interest of organic chemists since 1970s.However,the total syntheses of grayana...; 关键词：DITERPENOIDS bioinspired total syntheses divergent total syntheses Ni-catalyzed intramolecular Pauson–Khand reaction

Diterpenoids from Mangrove Plant Excoecaria agallocha L.and Their Anti-neuroinflammatory Activities: 《有机化学》2024年第11期3526-3530,共5页Junyi Li Lu Yang Mingbin Chen Yong Rao Zhongping Jiang Ling Huang; 国家自然科学基金(Nos.82204275,8216065);海南省自然科学基金(No.323MS014)资助项目。; Normal-phase and reversed-phase silica gel column chromatography and semi-preparative high performance liquid chromatography were applied to study the chemical constituents of the stems and twigs of the Hainan mangrov...; 关键词：Excoecaria agallocha L. mangrove plant kaurane diterpenoid labdane diterpenoid anti-neuroimflamation

Engineering the microenvironment of P450s to enhance the production of diterpenoids in Saccharomyces cerevisiae被引量：1: 《Acta Pharmaceutica Sinica B》2024年第10期4608-4618,共11页Yatian Cheng Linglong Luo Hao Tang Jian Wang Li Ren Guanghong Cui Yujun Zhao Jinfu Tang Ping Su Yanan Wang Yating Hu Ying Ma Juan Guo Luqi Huang; supported by the National Key R&D Program of China(2020YFA0908000);Scientific and technological innovation project of China Academy of Chinese Medical Sciences(CI2023D002,CI2023E002,CI2021A04110,CI2021B014);the National Natural Science Foundation of China(81822046);Key project at central government level:The ability to establish sustainable use of valuable Chinese medicine resources(2060302).; Cytochrome P450 enzymes play a crucial role as catalysts in the biosynthesis of numerous plant natural products(PNPs).Enhancing the catalytic activity of P450s in host microorganisms is essential for the efficient pro...; 关键词：Saccharomyces cerevisiae Metabolic engineering P450s TANSHINONES 11 20-Dihydroxyferruginol

Double-barreled defense: dual ent-miltiradiene synthases in most rice cultivars: 《aBIOTECH》2024年第3期375-380,共6页Yiling Feng Tristan Weers Reuben J.Peters; supported by grants from the NIH(GM131885)and USDA(2020-67013-32557)to R.J.P.; Rice(Oryza sativa)produces numerous diterpenoid phytoalexins that are important in defense against pathogens.Surprisingly,despite extensive previous investigations,a major group of such phytoalexins,the abietoryzins,w...; 关键词：PHYTOALEXINS DITERPENOIDS Diterpene synthases Tandem gene duplication NEOFUNCTIONALIZATION

Discovery of antitumor diterpenoids from Casearia graveolens targeting VEGFR-2 to inhibit angiogenesis: 《Chinese Journal of Natural Medicines》2024年第9期842-853,共12页WANG Sibei LIU Yuhui LIANG Yue XI Yaru ZHAI Yupeng LEE Dongho XU Jing GUO Yuanqiang; supported by the National Natural Science Foundation of China(No.22077067);the Project of State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University[No.QJJ(2022)422];the 111 Project(No.B20016)。; Eight novel clerodane diterpenoids(1-8)were isolated from the twigs of Casearia graveolens.Their structures were elucidated through comprehensive nuclear magnetic resonance(NMR),high-resolution electrospray ionization...; 关键词：Clerodane diterpenoids Casearia graveolens Surface plasmon resonance Vascular endothelial growth factor receptor 2 Antitumor activity ZEBRAFISH

Insight of Natural Compounds Halimane Diterpenoids against Mycobacterium tuberculosis: Virtual Screening, DFT, Drug-Likeness, and Molecular Dynamics Approach: 《Computational Molecular Bioscience》2024年第2期35-58,共24页Laurent Gael Eyia Andiga Boris Davy Bekono Désiré Mama Bikele Pie Pascal Onguéné Amoa Luc Calvin Owono Owono Luc Léonard Mbaze Meva’a; In the purpose to design novel antituberculosis (anti-TB) drugs agents against Mycobacterium tuberculosis (Mtb), we have built a molecular library around 42 Halimane Diterpenoids isolated from natural sources. Two Mtb...; 关键词：Antituberculosis Druglikeness Density Functional Theory Halimane Diterpenoids Molecular Docking Molecular Dynamics Simulation

New pimarane diterpenoids with antibacterial activity from fungus Arthrinium sp.ZS03: 《Chinese Journal of Natural Medicines》2024年第4期356-364,共9页ZHAO Songfeng JING Ziwei; supported by the National Natural Science Foundation of China(No.82003956);the Henan Young Elite Scientists Sponsorship Program(No.2023HYTP032)。; A comprehensive chemical study of the endophytic fungus Arthrinium sp. ZS03, associated with Acorus tatarinowii Schott, yielded eleven pimarane diterpenoids (compounds 1–11), including seven novel compounds designate...; 关键词：Arthrinium sp.ZS03 Pimarane diterpenoids Structural elucidation Antibacterial activity

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DITERPENOIDS

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DITERPENOIDS

检索结果分析

下载全文

用户登录

高级检索检索式检索