The Genus Solanum:An Ethnopharmacological,Phytochemical and Biological Properties Review  

作　　者：Joseph Sakah Kaunda Ying-Jun Zhang 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204,People’s Republic of China [2]Graduate School of the Chinese Academy of Sciences,Beijing 100039,People’s Republic of China [3]Yunnan Key Laboratory of Natural Medicinal Chemistry,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2019年第2期77-137,共61页应用天然产物（英文）

摘　　要：Over the past 30 years,the genus Solanum has received considerable attention in chemical and biological studies.Solanum is the largest genus in the family Solanaceae,comprising of about 2000 species distributed in the subtropical and tropical regions of Africa,Australia,and parts of Asia,e.g.,China,India and Japan.Many of them are economically signifcant species.Previous phytochemical investigations on Solanum species led to the identifcation of steroidal saponins,steroidal alkaloids,terpenes,favonoids,lignans,sterols,phenolic comopunds,coumarins,amongst other compounds.Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to diferent tumors as breast cancer(4T1 and EMT),colorectal cancer(HCT116,HT29,and SW480),and prostate cancer(DU145)cell lines.The biological activities have been attributed to a number of steroidal saponins,steroidal alkaloids and phenols.This review features 65 phytochemically studied species of Solanum between 1990 and 2018,fetched from SciFinder,Pubmed,ScienceDirect,Wikipedia and Baidu,using“Solanum”and the species’names as search terms(“all felds”).

关 键 词：SOLANUM SOLANACEAE PHYTOCHEMISTRY Steroidal saponins and alkaloids ETHNOPHARMACOLOGY 

分 类 号：R73[医药卫生—肿瘤]