梅花化学成分与药理活性研究进展  

Advances in studies on chemical compositions and pharmacological activities of Mume Flos

作　　者：严辉[1] 蓝锦珊 濮宗进 郭盛[1] 李思蒙[1] 周桂生[1] 陈佩东[1] 詹志来 段金廒[1] YAN Hui;LAN Jin-shan;PU Zong-jin;GUO Sheng;LI Si-meng;ZHOU Gui-sheng;CHEN Pei-dong;ZHAN Zhi-lai;DUAN Jin-ao(National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae InnovativeMedicine,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,Jiangsu Key Laboratoryfor High Technology Research of Traditional Chinese Medicine Formulae,Nanjing University of Chinese Medicine,Nanjing210023,China;State Key Laboratory of Dao-di Herbs Breeding Base,National Resource Center for Chinese Materia Medica,China Academy ofChinese Medical Sciences,Beijing 100700,China)

机构地区：[1]南京中医药大学中药资源产业化与方剂创新药物国家地方联合工程研究中心/江苏省中药资源产业化过程协同创新中心/江苏省方剂高技术研究重点实验室,江苏南京210023 [2]中国中医科学院中药资源中心道地药材国家重点实验室培育基地,北京100700

出　　处：《中草药》2021年第11期3453-3461,共9页Chinese Traditional and Herbal Drugs

基　　金：中央本级重大增减支项目(2060302);财政部和农业农村部:国家现代农业产业技术体系资助(CARS-21);2019年医疗服务与保障能力提升补助资金“全国中药资源普查项目”(财社〔2019〕39号)。

摘　　要：梅花Mume Flos是中医临床上常用的花类药材之一,含有黄酮类、挥发油、苯丙素类、有机酸等成分,具有抗氧化、抗抑郁、抗黑色素生成和抗血小板凝集的现代药理作用。对近十几年来梅花主要化学成分及其药理作用的研究进展进行整理总结,为明确梅花现代药用价值和制定科学的质量标准评价提供基础,为梅花的深入研究和开发利用提供依据。The flower of plant Prunus mume is one of the most used flower medicinal materials in clinic. Mume Flos contains flavonoids,volatile oils,phenylpropanoids,organic acids and so on. It has been reported that Mume Flos has many modern pharmacological activities such as anti-oxidation,anti-depression,anti-melanogenesis,and anti-platelet aggregation. This article summarized the research progress on the main chemical components of Mume Flos and pharmacological effects,which provides a basis for clarifying the modern value of Mume Flos and formulating scientific quality evaluation standard,and provides a basis for in-depth research,development and utilization of Mume Flos.

关 键 词：梅花 黄酮类 苯丙素类 抗氧化 抗抑郁 

分 类 号：R286[医药卫生—中药学]