不同宫腔镜技术对育龄期患者多发子宫肌瘤疗效及对性激素和妊娠结局影响  

Clinical efficacy of different hysteroscopy technology for treating childbearing age women with multiple myoma of uterus and its influence on their sex hormone levels and pregnancy outcomes

作　　者：王秀梅 苗叶 佟亚菲 孙慧君 韩燕妮 李星星 杨芳 梁新新 WANG Xiumei;MIAO Ye;TONG Yafei;SUN Huijun;HAN Yanni;LI Xingxing;YANG Fang;LIANG Xinxin(Tangdu Hospital affiliated to Air Force Military Medical University,Shannxi Province,710038)

机构地区：[1]空军军医大学第二附属医院唐都医院,西安710038

出　　处：《中国计划生育学杂志》2021年第5期997-999,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨不同宫腔镜技术对育龄期多发子宫肌瘤患者疗效及对性激素和妊娠结局影响。方法:选取本科收治的89例育龄期子宫肌瘤患者,根据治疗方式分别采用宫腔镜冷刀切除治疗(冷刀组)或传统宫腔镜电切技术治疗(电切组),比较两组临床疗效。结果:冷刀组手术时间(51.3±4.4min)、术中出血量(50.0±2.8ml)、术后排气时间(33.5±4.0h)、住院时间(7.2±1.0d)均优于电切组(P<0.05);治疗后两组相关性激素指标均得到改善但两组间无差异(P>0.05),冷刀组炎性指标白细胞介素-6(29.3±4.3 ng/ml)及C反应蛋白(25.2±1.8 mg/L)改善情况优于电切组(P<0.05);术后18个月后,冷刀组妊娠率(95.6%)高于电切组(81.8%)(P<0.05)。结论:宫腔镜冷刀切除治疗对育龄期多发子宫肌瘤患者的疗效更佳,可更好改善性激素、炎性指标及妊娠结局。Objective: To investigate the clinical efficacy of different hysteroscopy technology for treating childbearing age women with multiple myoma of uterus, and to study its influence on their sex hormone levels and pregnancy outcomes. Methods: 89 childbearing age women with multiple myoma of uterus were selected as research subjects and were divided into study group(45 cases experinced hysteroscopic cold knife resection) and control group(44 cases experienced traditional hysteroscopy electric knife excision). The clinical efficacy of the women was compared between the two groups. Results: The operative time(51.3±4.4 min), intraoperative blood loss(50.0±2.8 ml), postoperative exhaust time(33.5±4.0 h), and hospital stay(7.2±1.0 d) of the women in the study group were significant better than those of the women in the control group(P<0.05). After treatment, the related sex hormone levels of the women in both groups had improved significantly, but which had no significant differences between the two groups(P>0.05). The improvement degrees of inflammatory indexes, such as interleukin-6 level(29.3±4.3 ng/mL) and C-reactive protein level(25.2±1.8 mg/L) of the women in the study group were significant better than those of the women in the control group(P<0.05). 18 months after operation, the pregnancy rate(95.6%) of the women in the study group was significant higher than that(81.8%) of the women in the control group(P<0.05). Conclusion: The hysteroscopic cold knife resection for treating childbearing age women with multiple myoma of uterus is better efficacy, which can better improve the levels of sex hormones and inflammatory indexes, and pregnancy outcomes.

关 键 词：育龄期女性 多发子宫肌瘤 宫腔镜技术 冷刀 疗效 妊娠结局 

分 类 号：R737.33[医药卫生—肿瘤]