吲哚菁绿在生物成像与医学工程中的应用进展  

Application of Indocyanine Green in Bioimaging and Medical Engineering

作　　者：周巧雨 许佳佳 刘敏 马鑫 黄雨柔 吴彦东[1] 陈琼[1] 尹军[1] ZHOU Qiaoyu;XU Jiajia;LIU Min;MA Xin;HUANG Yurou;WU Yandong;CHEN Qiong;YIN Jun(Key Laboratory of Pesticide and Chemical Biology,Ministry of Education,College of Chemistry,Central China Normal University,Wuhan 430079,Hubei,P.R.China)

机构地区：[1]华中师范大学化学学院农药与化学生物学教育部重点实验室,湖北武汉430079

出　　处：《影像科学与光化学》2021年第4期487-491,共5页Imaging Science and Photochemistry

基　　金：华中师范大学实验室研究项目(201984);2020年华中师范大学大学生创新创业训练计划项目。

摘　　要：吲哚菁绿(ICG)是一种阳离子型花菁类染料,具有毒性低、亲和力高、荧光发射位于近红外区等优点。因此,作为一种可临床使用的近红外有机荧光染料,其已被广泛应用于生物成像、疾病诊断等领域。本文从吲哚菁绿的临床应用和肿瘤诊断治疗展开论述,通过实例全面介绍ICG的相关信息。Indocyanine green(ICG),a cationic cyanine dye,has the advantages of low toxicity,high affinity and near-infrared emission.Therefore,as a kind of near-infrared organic fluorescent dye which can be used in clinical medicine,it has been widely applied in biological imaging,disease diagnosis and other fields.In this paper,the clinical application and tumor diagnosis and treatment of indocyanine green were discussed,and the relevant information about ICG was comprehensively introduced through examples.

关 键 词：吲哚菁绿 荧光染料 生物成像 诊断与治疗 

分 类 号：R318[医药卫生—生物医学工程] Q-334[医药卫生—基础医学]