造影增强超声内镜与增强CT对胰腺实性占位诊断价值的比较分析  

Value of contrast-enhanced endoscopic ultrasound versus contrast-enhanced computed tomography in the diagnosis of pancreatic solid space-occupying lesions

作　　者：李静[1] 李鑫[1] 张辉[1] 徐有青[1] LI Jing;LI Xin;ZHANG Hui;XU Youqing(Department of Gastroenterology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院消化内科,北京100070

出　　处：《临床肝胆病杂志》2021年第7期1648-1651,共4页Journal of Clinical Hepatology

基　　金：首都医学发展科研基金(首发2020-1-2042)。

摘　　要：目的探讨造影增强超声内镜(CE-EUS)与增强CT(CE-CT)对胰腺实性占位的诊断价值。方法选取2014年1月—2019年12月就诊于首都医科大学附属北京天坛医院的胰腺实性占位患者78例,所有患者均经EUS引导下细针抽吸活检或手术后病理确诊,比较CE-EUS、CE-CT诊断胰腺实性占位的准确率、敏感度、特异度、Youden指数。结果CE-EUS、CE-CT诊断胰腺癌的正确率分别为97.9%、87.2%,敏感度分别为97.7%、88.9%,特异度分别为100%、50%,Youden指数分别为0.96、0.76;CE-EUS、CE-CT诊断小胰癌的准确率分别为84.6%、61.5%,敏感度分别为80%、70%,特异度分别为100%、33.3%,Youden指数分别为0.80、0.03;CE-EUS、CE-CT诊断慢性胰腺炎肿块的准确率分别为90.5%、61.9%,敏感度分别为94.1%、64.7%,特异度分别为75%、50%,Youden指数分别为0.69、0.15;CE-EUS、CE-CT诊断胰腺神经内分泌肿瘤的准确率分别为85.7%、28.6%,敏感度分别为83.3%、16.7%,特异度分别为100%、100%,Youden指数分别为0.83、0.17。结论在对胰腺实性占位的诊断方面,CE-EUS较CE-CT有明显优势。Objective To investigate the value of contrast-enhanced endoscopic ultrasound(CE-EUS)versus contrast-enhanced computed tomography(CE-CT)in the diagnosis of pancreatic solid space-occupying lesions.Methods A total of 78 patients with pancreatic solid space-occupying lesions who attended Beijing Tiantan Hospital,Capital Medical University,from January 2014 to December 2019 were enrolled.All patients were diagnosed by EUS-guided fine needle aspiration or postoperative pathology,and CE-EUS and CE-CT were compared in terms of their accuracy,sensitivity,specificity,and Youden index in the diagnosis of pancreatic solid space-occupying lesions.Results In the diagnosis of pancreatic cancer,CE-EUS and CE-CT had accuracy rates of 97.9%and 87.2%,sensitivities of 97.7%and 88.9%,specificities of 100%and 50%,and Youden indices of 0.96 and 0.76,respectively.In the diagnosis of small pancreatic cancer,CE-EUS and CE-CT had accuracy rates of 84.6%and 61.5%,sensitivities of 80%and 70%,specificities of 100%and 33.3%,and Youden indices of 0.80 and 0.03,respectively.In the diagnosis of chronic pancreatitis with mass,CE-EUS and CE-CT had accuracy rates of 90.5%and 61.9%,sensitivities of 94.1%and 64.7%,specificities of 75%and 50%,and Youden indices of 0.69 and 0.15,respectively.In the diagnosis of pancreatic neuroendocrine tumors,CE-EUS and CE-CT had accuracy rates of 85.7%and 28.6%,sensitivities of 83.3%and 16.7%,specificities of 100%and 100%,and Youden indices of 0.83 and 0.17,respectively.Conclusion CE-EUS has certain advantages over CE-CT in the diagnosis of pancreatic solid space-occupying lesions.

关 键 词：胰腺肿瘤 内分泌腺肿瘤 腔内超声检查 体层摄影术 X线计算机 诊断 

分 类 号：R735.9[医药卫生—肿瘤]