水产动物模型的建立及在病害防控上的研究进展  

Establishment of Aquatic Animal Model and Its Application in Disease Control

作　　者：陈佳明 王庆[1] 王英英[1] 曾伟伟 尹纪元 李莹莹[1] Chen Jiaming;Wang Qing;Wang Yingying;Zeng Weiwei;Yin Jiyuan;Li Yingying(Pearl River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Key Laboratory of Fishery Drug Development of Ministry of Agriculture and Rural Affairs,Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province,Guangzhou 510380,China;College of Fisheries and Life Science,Shanghai Ocean University,Shanghai 201306,China;School of Life Science and Engineering,Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding,Key Laboratory of Animal Molecular Design and Precise Breeding of Higher Education Institute,Foshan Univesity,Foshan 440605,China)

机构地区：[1]中国水产科学研究院珠江水产研究所,农业农村部渔药创制重点实验室,广东省水产动物免疫技术重点实验室,广州510380 [2]上海海洋大学水产与生命学院,上海201306 [3]佛山科学技术学院,广东省动物分子设计与精准育种重点实验室,普遍高校动物分子设计与精准育种重点实验室,生命科学与工程学院,佛山440605

出　　处：《生态毒理学报》2021年第2期119-126,共8页Asian Journal of Ecotoxicology

基　　金：国家自然科学基金资助项目(31602202);中国水产科学研究院基本科研业务费资助项目(2020XT0403);广东省现代农业产业技术体系创新团队建设专项资金资助项目(2021KJ150);国家大宗淡水鱼产业技术体系(CARS-45)。

摘　　要：近年来,水产动物模型在鱼病防控方面的应用越来越广泛。其具备遗传背景清晰、条件可控性强等优点,是鱼病防控基础研究的有效工具之一。本文论述了水产动物模型的建立方法以及在鱼类疾病病原分析、疫苗开发和水质监测方面应用的研究现状,并对水产动物替代模型的发展前景做了简要论述。In recent years,aquatic animal models have been widely used in the area of prevention and control of fish diseases.It has the clear genetic background of the used animals,strong controllability and thus can be an effective tool for basic research of fish disease prevention and control.In this paper,the establishment of aquatic animal model and its application for pathogen analysis of fish diseases,vaccine development and water quality monitoring were discussed,and the development prospect of aquatic animal experimental model was also mentioned.

关 键 词：动物模型 病原分析 疫苗开发 水质监测 

分 类 号：X171.5[环境科学与工程—环境科学]