同步放化疗中晚期宫颈癌预后因素分析  

Effects of concurrent radiochemotherapy on advanced and intermediate-stage cervical cancer and its prognosis predictors

作　　者：傅华 李莎 张超 任正华 田种泽 刘艳 FU Hua;LI Sha;ZHANG Chao;REN Zhenghua;TIAN Zhongze;LIU Yan(The 940th Hospital of Joint Logistic Support Force of PLA,Department of Radiontherapy,Lanzhou 730050,China;The 940th Hospital of Joint Logistic Support Force of PLA,Department of Health Service,Lanzhou 730050,China)

机构地区：[1]解放军联勤保障部队第940医院放疗科,甘肃兰州730050 [2]解放军联勤保障部队第940医院卫勤部,甘肃兰州730050

出　　处：《西北国防医学杂志》2021年第5期352-355,共4页Medical Journal of National Defending Forces in Northwest China

基　　金：原兰州军区医药卫生科研计划项目(CLZ15JA03)。

摘　　要：目的:探讨同步放化疗中晚期宫颈癌预后的影响因素。方法:回顾性分析我院2005-01~2013-12采取同步放化疗治疗的145例中晚期宫颈癌患者的临床资料,分析影响同步放化疗中晚期宫颈癌预后的因素。结果:全组患者因宫颈癌死亡64例。1、3、5年生存率分别为98.6%、80.0%、66.9%,中位生存时间69个月。单因素分析显示:患者的生存率与年龄、FIGO临床分期、病理类型、分化程度、肿瘤直径、绝经情况、治疗前血红蛋白含量均有相关性。Cox回归分析显示,年龄、FIGO临床分期、病理类型、分化程度、绝经情况、治疗前血红蛋白含量是影响中晚期同步放化疗宫颈癌患者预后的独立危险因素。结论:年龄、FIGO临床分期、病理类型、分化程度、绝经情况、治疗前血红蛋白含量可能是影响中晚期同步放化疗宫颈癌预后的因素。Objective:To explore the survival of patients with cervical cancer and analyze the prognostic factors.Methods:Patients with cervical cancer(145 cases)treated in our hospital from January 2005 to December 2013 were reviewed and followed up to explore the survival of patients with cervical cancer and analyze the prognostic factors.Results:There were 64 patients died of cervical cancer.The 1,3,and 5-year survival were 98.6%、80.0%、66.9%respectively,the median survival was 69 months.Univariate analysis showed that survival was related to age,FIGO(federation international of gynecology and obsteterics)clinical staging,histological classification,diameter of differentiation,diameter of tumor,menopause,hemoglobin.Multivariate analysis showed that the age,FIGO clinical staging,histological classification,diameter of differentiation,diameter of tumor,menopause,hemoglobinwere independent prognostic factors that influenced survival rates of patients.Conclusion:Age,FIGO clinical staging,histological classification,diameter of differentiation,diameter of tumor,menopause,hemoglobin may be prognostic factors of patients with cervical cancer.

关 键 词：宫颈癌 预后 生存分析 

分 类 号：R737.33[医药卫生—肿瘤]