光学相干层析成像技术在肿瘤诊疗方面的应用  

Application of optical coherency tomography in tumor diagnosis and treatment

作　　者：杨建凯[1] 霍浩然[1] 孙国柱[1] 范振增[1] 焦保华[1] Yang Jiankai;Huo Haoran;Sun Guozhu;Fan Zhenzeng;Jiao Baohua(Department of Neurosurgery,Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院神经外科,石家庄050000

出　　处：《国际肿瘤学杂志》2021年第5期287-291,共5页Journal of International Oncology

基　　金：京津冀基础研究合作专项研究项目(19JCZDJC65300(Z));河北省科技厅-河北医科大学"厅校会商基金-科技创新"项目(2020TXJC08);河北医科大学第二医院院级课题(2HC202010)。

摘　　要：光学相干层析成像(OCT)是一种功能强大的光学成像,能够对活体生物组织内部的微观结构进行高分辨率的横断面层析成像。随着OCT技术的迅猛发展,广大研究者进行了广泛的临床前和临床期肿瘤成像,从而对肿瘤复杂的生理、细胞和分子改变有了更深刻的理解。OCT的临床前研究已经阐明了肿瘤生物学中许多难以理解的方面,而OCT的临床应用正在彻底改变肿瘤的诊断和治疗。作为一种新型无创的检查方法,OCT技术可实现肿瘤的术中成像,提供有意义的图像资料,将为肿瘤的诊断、分级、边界判定提供巨大的帮助。Optical coherency tomography(OCT)is one of the powerful optical imaging tools that allows cross-sectional tomography of the microstructure in living subjects with high resolution.With the rapid development of OCT and a wide range of preclinical and clinical tumor imaging,it provides profound insights into the complex physiological,cellular and molecular behaviors of tumors.Preclinical OCT has elucidated many inscrutable aspects of tumor biology,while clinical applications of OCT are revolutionizing diagnosis and therapies.As a new noninvasive optical imaging technique,OCT can realize the intraoperative imaging of tumor and provide meaningful image data,which will provide great help for the diagnosis,classification and boundary determination of tumor diseases in the future.

关 键 词：肿瘤 诊断 治疗 光学相干层析成像 

分 类 号：R730.4[医药卫生—肿瘤]