尿酸检测方法的研究进展  

Research progress on uric acid detection methods

作　　者：江民川 赵阳[1] 马芳芳 张微 刘春叶[1] JIANG Minchuan;ZHAO Yang;MA Fangfang;ZHANG Wei;LIU Chunye(School of Pharmacy,Xi′an Medical University,Xi′an 710021,China)

机构地区：[1]西安医学院药学院,陕西西安710021

出　　处：《化工科技》2021年第3期75-79,共5页Science & Technology in Chemical Industry

基　　金：国家级大学生创新创业训练项目(202011840011);陕西省大学生创新创业训练项目(S202011840011);校级大学生创新创业训练项目(121520011)。

摘　　要：人体内尿酸含量与高尿酸血症、心脑血管疾病、Lesch-Nyhan综合症等疾病的发生发展密切相关,寻找快捷、方便、廉价、准确的尿酸检测方法,对上述疾病的预防和临床诊断具有重要意义。常见的尿酸检测方法有磷钨酸还原法、色谱法、分光光度法、电化学法、酶法等。这些方法各具优缺点,综述了尿酸检测方法,同时对检测新方法即微流控纸芯片法进行总结,以期能为尿酸检测方法的研究发展提供借鉴与参考。The uric acid content in human body is closely related to hyperuricemia,cardiovascular diseases,and Lesch Nyhan syndrome.It is necessary to develop a fast,convenient,economic and accurate method for the uric acid detection.It is beneficial to the prevention and diagnosis of the above diseases.There are many detection methods of uric acid,such as phosphotungstic acid reduction method,chromatography,spectrophotometry,electrochemical method,and enzyme method,etc.The paper reviewed these methods and introduced a novel uric acid detection method,microfluidic paper-based chip method.It can provide references for the research and development of uric acid detection.

关 键 词：尿酸检测 色谱法 电化学法 酶法 微流控纸芯片法 

分 类 号：R446.12[医药卫生—诊断学]