Gestational vitamin B supplementation alleviates neurodevelopmental abnormalities induced by PM2s in mice offspring  

作　　者：Wang Tingting Sun Lijuan Liu Chong Lyu Ying Zhang Tianliang Yu Li 

机构地区：[1]Department of Histology and Embryology,Weifang Medical University,Weifang 261053

出　　处：《解剖学杂志》2021年第S01期117-117,共1页Chinese Journal of Anatomy

摘　　要：Gestational exposure to PM25 leads to neurodevelopmental impairment in offsprings.However,no effective means has been found to alleviate the neurodevelopmental impairment of embryos induced by PM2s.To clarify the effects of vitamin B on anti-inflammatory,antioxidant,synaptic remodeling and neuroprotection,we used it in a mouse model simulating gestational exposure to PM2.s.We found that after vitamin B intervention,anxiety,depression,social communication disorders,stereotyped repetitive behavior,and learning/spatial memory were impaired in mice offsprings.

关 键 词：VITAMIN impaired IMPAIRMENT 

分 类 号：R28[医药卫生—中药学]