老年癌症病人握力与健康相关生命质量关系的研究  

Association between hand grip strength and health-related quality of life in elderly patients with cancer

作　　者：包蓓[1] 吴韫韬 石晓欣[1] 荣棣君 朱立人[1] 王燕[1] BAO Bei;SHI Xiao-xin;ZHU Li-ren;WANG Yan;WU Yun-tao;RONG Di-jun(Department of Geriatrics,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200093,China;Huayang Community Health Service Center of Changning District,Shanghai 200042,China;Quyang Community Health Service Center of Hongkou District,Shanghai 200437,China)

机构地区：[1]上海交通大学医学院附属新华医院老年科,上海市200093 [2]上海长宁区华阳街道社区卫生服务中心,上海市200042 [3]上海虹口区曲阳街道社区卫生服务中心,上海市200437

出　　处：《实用老年医学》2021年第7期718-721,共4页Practical Geriatrics

基　　金：上海交通大学中国医院发展研究院医院发展战略研究所项目(HDSI-2020-B-010)。

摘　　要：目的评估上海老年癌症病人的握力(HGS)与健康相关生活质量(HRQoL)之间的关系。方法对2019年3月1日至2020年3月31日我院以及上海长宁、虹口2个社区共1115例癌症病人进行横断面调查,测量HGS,使用EuroQol-5维度(EQ-5D)评估HRQOL,分析两者的相关性。结果共回收有效问卷983份,其中197例癌症病人HGS减弱(最低五分位数男性<29.7 kg,女性<19.7 kg)。与HGS正常的病人相比,HGS减弱的病人EQ-5D的5个维度的损害均有加重(P<0.05)。多因素Logistic回归分析显示,除焦虑/抑郁这一维度,HGS每增加1 kg,HRQoL在4个维度(活动能力、自理能力、日常活动和疼痛/不适)中均表现受损风险降低(P<0.05)。结论HGS增高可能提示老年癌症病人较好的HRQoL。Objective To assess the association between hand gripstrength(HGS)and health-related quality of life(HRQoL)among elderly patients with cancer in Shanghai.Methods A cross-sectional survey was conducted among 1115 elderly cancer survivors from our hospital,Shanghai Changning and Hongkou communities from March 2019 to March 2020.HGS was detected and the HRQoL was evaluated by EuroQol-5 dimension(EQ-5D)in all patients.The relationship between HGS and HRQoL was analyzed.Results Of 1115 questionnaires,983 were valid.Among 983 cancer survivors,197 cases showed weak HGS according to gender-specific cut-off values(lowest quintile<29.7 kg in men and<19.7 kg in women).Individuals with weak HGS showed significantly increased impairment in all five dimensions of the EQ-5D compared with the patients with normal HGS(P<0.05).The Logistic multiple factors regression analysis showed that the impaired risk were all decreaed in four dimensions(mobility,self-care,usual activity and pain/discomfort)with the increase of HGS(P<0.05).Conclusions The increase of HGS may indicate better HRQoL in the elderly cancer patients.

关 键 词：老年人 癌症 握力 健康相关生命质量 

分 类 号：R73[医药卫生—肿瘤]