Enhanced cell transfection using subwavelength focused optical eigenmode beams[Invited]  

作　　者：Xanthi Tsampoula Michael Mazilu Tom Vettenburg Frank Gunn-Moore Kishan Dholakia 

机构地区：[1]SUPA,School of Physics and Astronomy,University of St.Andrews,St.Andrews KY169SS,UK [2]School of Biology,Medical and Biological Science Building,University of St.Andrews,St.Andrews,North Haugh,Fife KY169TF,UK

出　　处：《Photonics Research》2013年第1期42-46,共5页光子学研究（英文版）

摘　　要：We show that superoscillating light fields,created using the method of optical eigenmodes,enable more efficient multiphoton-mediated cell transfection.Chinese hamster ovary cells are transfected with a plasmid and exhibit expression of DsRed-Mito in the mitochondria.We demonstrate an efficiency improvement of 35%compared to the diffraction-limited spot.This opens up new vistas for nanoscale localized cell transfection.

关 键 词：enable OSCILLATING EIGEN 

分 类 号：R73[医药卫生—肿瘤]