Nd∶YAP激光联合宝氟锐脱敏剂对牙本质小管封闭效果的研究  

Occluding effect of Nd∶YAP laser irradiation combined with profluorid varnish on dentinal tubules

作　　者：金婕 沈烨青 杜嵘[1] 朱亚琴[1] JIN Jie;SHEN Yeqing;DU Rong;ZHU Yaqin(Department of General Dentistry,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,College of Stomatology,Shanghai Jiao Tong University,National Center for Stomatology,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology,China,200011)

机构地区：[1]上海交通大学医学院附属第九人民医院口腔综合科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,200011

出　　处：《实用口腔医学杂志》2021年第4期557-560,共4页Journal of Practical Stomatology

基　　金：国家自然科学基金(编号:81271134)。

摘　　要：目的:比较Nd∶YAP激光、宝氟锐脱敏剂以及联合使用对牙本质小管封闭效果。方法:选择牙体完整且无龋坏的第三恒磨牙制备50个牙本质过敏症模型,随机分为5组(n=10):A组(空白对照组),B组(宝氟锐组),C组(Nd∶YAP激光组),D组(Nd∶YAP激光+宝氟锐组),E组(宝氟锐+Nd∶YAP激光组),各组样本分别处理后用扫描电子显微镜观察牙本质小管形态,使用Image-Pro Plus测量牙本质小管口的直径和相对面积。结果:各组间的牙本质小管口的直径与相对面积均为D组<E组<C组<B组<A组(P<0.05)。结论:Nd∶YAP激光与宝氟锐脱敏剂均具有封闭牙本质小管的作用;单独使用时,Nd∶YAP激光的效果优于宝氟锐脱敏剂;联合使用可能形成协同作用;先使用Nd∶YAP激光照射后涂布宝氟锐脱敏剂对牙本质小管的封闭效果更好。Objective:Tocompare and evaluate the occluding effect between Nd∶YAP laser,Profluorid Varnish,and their combined use on dentinal tubules.Methods:50 dentin sensitive models were prepared with the third permanent molars without defect or caries,all samples were randomly divided into 5 groups(n=10),group A(blank control),B(Profluorid Varnish),C(Nd∶YAP laser),D(Nd∶YAP laser+Profluorid Varnish)and E(Profluorid Varnish+Nd∶YAP laser).After treatment the morphological changes of dentin surface were observed under SEM,the diameter and relative area of the dentin tuble orifices were measured by of Image-Pro Plus image analysis software.Results:The diameter and relative area of the dentinal tubule orifices were as following:group D<group E<group C<group B<group A(P<0.05).Conclusion:Both Nd∶YAP laser and Profluorid Varnish have the function of occluding dentinal tubules;Nd∶YAP laser is more effective than Profluorid Varnish;combination of the 2 may produce a synergy fuction by application of Profluorid Varnish after Nd∶YAP laser irradiation.

关 键 词：Nd∶YAP激光 宝氟锐 牙本质小管 封闭效果 牙本质过敏症 

分 类 号：R781.2[医药卫生—口腔医学]